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Articles Published Processes
10/24/2023 8:39:24 AM | Browse: 341 | Download: 622
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Received |
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2023-07-31 18:04 |
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Peer-Review Started |
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2023-07-31 18:07 |
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To Make the First Decision |
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Return for Revision |
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2023-08-22 22:40 |
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Revised |
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2023-09-23 11:34 |
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Second Decision |
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2023-10-07 02:49 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2023-10-08 07:39 |
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Articles in Press |
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2023-10-08 07:39 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2023-10-18 02:25 |
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Publish the Manuscript Online |
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2023-10-24 08:39 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Review |
| Article Title |
Challenges and dilemmas in pediatric hepatic Wilson’s disease
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Upasana Ghosh, Moinak Sen Sarma and Arghya Samanta |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Moinak Sen Sarma, MBBS, MD, Adjunct Associate Professor, Doctor, Doctor, Department of Pediatric Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences,, Raebareli Road, Lucknow 226014, India. moinaksen@yahoo.com |
| Key Words |
Wilson’s disease; Children; Hepatic Wilson disease; D-penicillamine; Trientine; Exchangeable copper |
| Core Tip |
Wilson’s disease is an important and common cause of chronic liver disease among children with multi-organ affection. There are various biochemical parameters that aid in making the diagnosis but are nonetheless fraught with limitations. Treatment is lifelong and it’s important to maintain adequate chelation while monitoring for its adverse effects. It is important to distinguish the adverse effects of chelators from the disease manifestations per se, as the management is diagonally opposite, for example, differentiating D-penicillamine-induced paradoxical neurological worsening from neurological manifestations of Wilson disease. This review discusses these challenges in making a diagnosis and treating pediatric hepatic Wilson’s disease. |
| Publish Date |
2023-10-24 08:39 |
| Citation |
Ghosh U, Sen Sarma M, Samanta A. Challenges and dilemmas in pediatric hepatic Wilson’s disease. World J Hepatol 2023; 15(10): 1109-1126 |
| URL |
https://www.wjgnet.com/1948-5182/full/v15/i10/1109.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v15.i10.1109 |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
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