8/26/2014 5:16:00 PM | Browse: 1074 | Download: 994
Publication Name | World Journal of Gastroenterology |
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Manuscript ID | 8739 |
Country | Italy |
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2014-05-28 11:45 |
ISSN | 1007-9327 (print) and 2219-2840 (online) |
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Open Access | |
Copyright | |
Article Reprints | For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247 |
Permissions | For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207 |
Publisher | Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website | http://www.wjgnet.com |
Category | Gastroenterology & Hepatology |
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Manuscript Type | Minireviews |
Article Title | Telomere and telomerase in chronic liver disease and hepatocarcinoma |
Manuscript Source | Unsolicited Manuscript |
All Author List | Lucia Carulli and Claudia Anzivino |
Funding Agency and Grant Number | |
Corresponding Author | Lucia Carulli, MD, PhD, Department of Biomedical, Metabolic and Neural Sciences. University of Modena and Reggio Emilia, Via Giardini 1355, 41126 Modena, Italy. lucia.carulli@unimore.it |
Key Words | Chromosomes; Telomere; Telomerase; Liver-cirrhosis; Hepatocarcinoma |
Core Tip | The pathogenesis of liver cirrhosis is not completely elucidated. Genetic predisposition may contribute to the development of cirrhosis and hepatocellular carcinoma (HCC). Evidence supporting the role of genetic factors as a risk for cirrhosis and the concept of telomere shortening as a genetic risk factor for chronic liver disease and HCC has been proposed. Here we review the literature on telomerase mutations, telomere shortening and liver disease including hepatocellular carcinoma. |
Publish Date | 2014-05-28 11:45 |
Citation | Carulli L, Anzivino C. Telomere and telomerase in chronic liver disease and hepatocarcinoma. World J Gastroenterol 2014; 20(20): 6287-6292 |
URL | http://www.wjgnet.com/1007-9327/full/v20/i20/6287.htm |
DOI | http://dx.doi.org/10.3748/wjg.v20.i20.6287 |
Full Article (PDF) | WJG-20-6287.pdf |
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Full Article (Word) | WJG-20-6287.doc |
Manuscript File | 8739-Review.doc |
Answering Reviewers | 8739-Answering review(s).pdf |
Copyright License Agreement | 8739-Copyright assignment.pdf |
Non-Native Speakers of English Editing Certificate | 8739-Language certificate.pdf |
Peer-review Report | 8739-Peer review(s).pdf |
Scientific Editor Work List | 8739-Scientific editor work list.doc |