Publication Name	World Journal of Clinical Cases
Manuscript ID	8741
Country	United States

Received	2014-01-05 10:47
Peer-Review Started	2014-01-05 12:15
To Make the First Decision	2014-02-27 09:27
Return for Revision	2014-03-06 10:49
Revised	2014-05-03 10:13
Second Decision	2014-06-11 14:14
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-06-11 14:33
Articles in Press	2014-06-11 14:33
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-08-01 08:29
Publish the Manuscript Online	2014-09-03 20:56

ISSN	2307-8960 (online)
Open Access
Copyright
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Category	Pathology
Manuscript Type	Case Report
Article Title	Desmoplastic small round cell tumor with atypical immunohistochemical profile and rhabdoid-like differentiation
Manuscript Source	Unsolicited Manuscript
All Author List	Li Liang, Nina Tatevian, Meenakshi Bhattacharjee, Kuojen Tsao and John Hicks
Funding Agency and Grant Number	Funding Agency Grant Number Department of Pathology, the University of Texas Health Science Center at Houston, United States
Corresponding Author	Nina Tatevian, MD, Associate Professor, Director, Department of Pathology and Laboratory Medicine, University of Texas Health Science Center at Houston, 6431 Fannin, MSB-2230, Houston, TX 77030, United States. nina.tatevian@uth.tmc.edu
Key Words	Desmoplastic small round cell tumor; Ultrastructure; Cytogenetics; Rhabdoid cells; EWSR1-WT1
Core Tip	We describe a case of desmoplastic small round cell tumor (DSRCT) with an atypical immunohistochemical profile and rhabdoid-like tumor cells on electron microscopy (EM). DSRCT typically expresses epithelial, mesenchymal and neural markers simultaneously. In this case, the neoplastic cells were positive only for vimentin, desmin and CD56 and negative for epithelial and other muscle markers. EM showed focal rhabdoid differentiation, but INI-1 (SNF-5/BAF47) demonstrated preservation of nuclear positivity in the neoplastic cells. Cytogenetic studies showed translocation t(11;22)(p13;q12) confirming an EWSR1-WT1 translocation characteristic for DSRCT, and t(1;15)(q11;p11.2) of unknown significance.
Publish Date	2014-09-03 20:56
Citation	Liang L, Tatevian N, Bhattacharjee M, Tsao K, Hicks J. Desmoplastic small round cell tumor with atypical immunohistochemical profile and rhabdoid-like differentiation. World J Clin Cases 2014; 2(8): 367-372
URL	http://www.wjgnet.com/2307-8960/full/v2/i8/367.htm
DOI	http://dx.doi.org/10.12998/wjcc.v2.i8.367

Full Article (PDF)	WJCC-2-367.pdf
Full Article (Word)	WJCC-2-367.doc
Manuscript File	8741-Review.doc
Answering Reviewers	8741-Answering reviewers.pdf
Copyright License Agreement	8741-Copyright assignment.pdf
Peer-review Report	8741-Peer review(s).pdf
Scientific Misconduct Check	8741-CrossCheck.jpg
Scientific Editor Work List	8741-Scientific editor work list.pdf