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Articles Published Processes
2/2/2024 9:42:16 AM | Browse: 277 | Download: 887
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Received |
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2023-08-17 02:25 |
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Peer-Review Started |
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2023-08-17 02:28 |
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First Decision by Editorial Office Director |
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2023-11-06 03:52 |
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Return for Revision |
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2023-11-06 10:48 |
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Revised |
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2023-11-24 06:54 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2023-12-22 02:45 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2023-12-22 06:00 |
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Articles in Press |
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2023-12-22 06:00 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2024-01-29 07:16 |
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Publish the Manuscript Online |
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2024-02-02 09:42 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Basic Study |
| Article Title |
Early results of the integrative epigenomic-transcriptomic landscape of colorectal adenoma and cancer
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
You-Wang Lu, Zhao-Li Ding, Rui Mao, Gui-Gang Zhao, Yu-Qi He, Xiao-Lu Li and Jiang Liu |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
81960504 |
| “Xingdian Talents” Support Project of Yunnan Province |
RLQB20200002 |
| Medical Discipline Reserve Talents of Yunnan Province |
H-2018015 |
| Applied Basic Research Projects-Union Foundation of Kunming Medical University |
2017FE467(-132) |
| Talent Introduction Project of Hubei Polytechnic University |
21xjz34R |
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| Corresponding Author |
Jiang Liu, PhD, Senior Scientist, Department of Reproduction and Genetics, The First Affiliated Hospital of Kunming Medical University, No. 295 Xichang Road, Kunming 650032, Yunnan Province, China. liujiang6787@163.com |
| Key Words |
Colorectal cancer; Epigenomic alteration; Transcriptome; Methylation-regulated differentially expressed genes |
| Core Tip |
Despite enhanced global methylation in colorectal cancer (CRC), both adenoma and CRC share similar methylation patterns. High-grade CRC tends to exhibit elevated methylation levels in gene promoter regions compared to those in low-grade CRC. The integration of gene expression data identified 14 methylation-regulated differentially expressed genes, with AGTR1 and NECAB1 methylation being prognostically significant. |
| Publish Date |
2024-02-02 09:42 |
| Citation |
Lu YW, Ding ZL, Mao R, Zhao GG, He YQ, Li XL, Liu J. Early results of the integrative epigenomic-transcriptomic landscape of colorectal adenoma and cancer. World J Gastrointest Oncol 2024; 16(2): 414-435
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| URL |
https://www.wjgnet.com/1948-5204/full/v16/i2/414.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v16.i2.414 |
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