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12/19/2023 1:19:33 PM | Browse: 110 | Download: 131
Publication Name World Journal of Psychiatry
Manuscript ID 87763
Country China
Received
2023-08-26 08:36
Peer-Review Started
2023-08-26 08:38
To Make the First Decision
Return for Revision
2023-09-05 03:30
Revised
2023-10-04 08:01
Second Decision
2023-11-03 09:25
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2023-11-09 06:46
Articles in Press
2023-11-09 06:46
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2023-12-08 05:15
Publish the Manuscript Online
2023-12-19 13:19
ISSN 2220-3206 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Psychiatry
Manuscript Type Case Control Study
Article Title Brain-derived neurotrophic factor, sex hormones and cognitive decline in male patients with schizophrenia receiving continuous antipsychotic therapy
Manuscript Source Unsolicited Manuscript
All Author List Jin Li, Wen-Huan Xiao, Fei Ye, Xiao-Wei Tang, Qiu-Fang Jia and Xiao-Bin Zhang
ORCID
Author(s) ORCID Number
Qiu-Fang Jia http://orcid.org/0009-0001-0980-6268
Xiao-Bin Zhang http://orcid.org/0000-0002-0577-5951
Funding Agency and Grant Number
Funding Agency Grant Number
the Suzhou Municipal Sci-Tech Bureau Program SS202070
Scientific and Technological Program of Suzhou SS202069
Suzhou clinical Medical Center for mood disorders Szlcyxzx202109
Suzhou Clinical Key Disciplines for Geriatric Psychiatry SZXK202116
Suzhou Key Technologies Program SKY2021063
Jiangsu Province social development project BE2020764
Research Project of Jiangsu Commission of Health M2020031
Elderly Health Research Project of Jiangsu Commission of Health LR2022015
Elderly Health Research Project of Jiangsu Commission of Health LKZ2023020
Corresponding Author Xiao-Bin Zhang, MD, PhD, Chief Physician, Department of Psychiatry, The Affiliated Guangji Hospital of Soochow University, No. 11 Guangqian Road, Suzhou 215137, Jiangsu Province, China. zhangxiaobim@163.com
Key Words Brain-derived neurotrophic factor; Clinical symptoms; Cognitive function; Schizophrenia; Sex hormones
Core Tip Brain-derived neurotrophic factor (BDNF) and sex hormones are known to be involved to the psychopathology of schizophrenia (SCZ). However, the influence of BDNF and sex hormones on cognition and symptoms in chronic antipsychotic-treated male (CATM) SCZ patients have yet to be investigated. Testosterone, prolactin (PRL) and luteinizing hormone were significantly higher in the patient group than in the healthy controls while estradiol (E2) levels were significantly lower. Analysis also identified positive correlations between E2 levels and BDNF levels, and BDNF levels and the digital cancellation time, in the whole sample. we found significant correlations between PRL levels and negative symptoms score in CATM patients with SCZ.
Publish Date 2023-12-19 13:19
Citation Li J, Xiao WH, Ye F, Tang XW, Jia QF, Zhang XB. Brain-derived neurotrophic factor, sex hormones and cognitive decline in male patients with schizophrenia receiving continuous antipsychotic therapy. World J Psychiatry 2023; 13(12): 995-1004
URL https://www.wjgnet.com/2220-3206/full/v13/i12/995.htm
DOI https://dx.doi.org/10.5498/wjp.v13.i12.995
Full Article (PDF) WJP-13-995-with-cover.pdf
Full Article (Word) WJP-13-995.docx
STROBE Statement 87763-STROBE statement.pdf
Manuscript File 87763_Auto_Edited-JLW.docx
Answering Reviewers 87763-Answering reviewers.pdf
Audio Core Tip 87763-Audio core tip.mp3
Biostatistics Review Certificate 87763-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 87763-Conflict-of-interest statement.pdf
Copyright License Agreement 87763-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 87763-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) 87763-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 87763-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 87763-Language certificate.pdf
Peer-review Report 87763-Peer-review(s).pdf
Scientific Misconduct Check 87763-Bing-Lin C-2.png
Scientific Editor Work List 87763-Scientific editor work list.pdf