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Articles Published Processes
11/22/2023 4:14:47 AM | Browse: 155 | Download: 619
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Received |
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2023-08-28 07:23 |
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Peer-Review Started |
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2023-08-28 07:26 |
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To Make the First Decision |
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Return for Revision |
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2023-09-14 07:15 |
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Revised |
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2023-09-20 07:51 |
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Second Decision |
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2023-10-17 08:39 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2023-10-23 07:32 |
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Articles in Press |
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2023-10-23 07:32 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2023-10-16 22:12 |
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Typeset the Manuscript |
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2023-11-14 05:02 |
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Publish the Manuscript Online |
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2023-11-22 04:14 |
| ISSN |
2218-4333 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Basic Study |
| Article Title |
Computational exploration of the significance of COPS6 in cancer: Functional and clinical relevance across tumor types
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Shi-Lin Wang, Guang-Zheng Zhuo, Li-Ping Wang, Xiang-Hu Jiang, Guo-Hong Liu, Yun-Bao Pan and Yi-Rong Li |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
31900558 |
| the Hubei Provincial Youth Talents Program for Public Health |
WSJKRC2022013 |
| Wuhan Young and Middle-Aged Medical Backbone Talents Training Project |
WHQG201904 |
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| Corresponding Author |
Yi-Rong Li, N/A, Professor, Department of Laboratory Medicine, Zhongnan Hospital of Wuhan University, No. 169 Donghu Road, Wuchang District, Wuhan 430071, Hubei Province, China. liyirong2021@126.com |
| Key Words |
COPS6; Biomarker; Tumor mutational burden; Immune infiltration; Prognostic analysis |
| Core Tip |
COPS6 has been implicated in several cancer types. However, its precise role in most cancer types remains poorly understood. Therefore, we aimed to investigate the function of COPS6 in various tumor types. Through our analysis, we discovered that COPS6 is highly expressed and associated with high-risk profiles in most cancers. Meanwhile, COPS6 expression was positively correlated with tumor mutation burden, microsatellite instability, and immune infiltration of the tumor microenvironment. Our findings suggest that COPS6 could be a potential biomarker for cancer research. Our study contributes to the understanding of the role of COPS6 in cancer progression and highlights the clinical applications. |
| Publish Date |
2023-11-22 04:14 |
| Citation |
Wang SL, Zhuo GZ, Wang LP, Jiang XH, Liu GH, Pan YB, Li YR. Computational exploration of the significance of COPS6 in cancer: Functional and clinical relevance across tumor types. World J Clin Oncol 2023; 14(11): 479-503 |
| URL |
https://www.wjgnet.com/2218-4333/full/v14/i11/479.htm |
| DOI |
https://dx.doi.org/10.5306/wjco.v14.i11.479 |
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