Publication Name	World Journal of Gastroenterology
Manuscript ID	87853
Country	China

Received	2023-10-26 03:12
Peer-Review Started	2023-10-26 03:12
To Make the First Decision
Return for Revision	2023-11-13 08:37
Revised	2023-11-22 09:41
Second Decision	2023-12-05 23:57
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2023-12-13 07:31
Articles in Press	2023-12-13 07:31
Publication Fee Transferred
Edit the Manuscript by Language Editor	2023-12-19 19:29
Typeset the Manuscript	2024-01-04 05:47
Publish the Manuscript Online	2024-01-06 12:15

ISSN	1007-9327 (print) and 2219-2840 (online)
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Category	Microbiology
Manuscript Type	Basic Study
Article Title	Mechanistic research: Selenium regulates virulence factors, reducing adhesion ability and inflammatory damage of Helicobacter pylori
Manuscript Source	Unsolicited Manuscript
All Author List	Chun Qin, Gan-Rong Huang, Ai-Xing Guan, Wen-Ting Zhou, Hao Chen, Pei-pei Luo, Xian-Ke Luo, Yan-Qiang Huang and Zan-Song Huang
ORCID	Author(s) ORCID Number Chun Qin http://orcid.org/0000-0002-7922-5071 Gan-Rong Huang http://orcid.org/0000-0001-5580-8689 Ai-Xing Guan http://orcid.org/0009-0007-7409-941X Wen-Ting Zhou http://orcid.org/0009-0004-0575-1126 Hao Chen http://orcid.org/0000-0003-0760-3552 Pei-pei Luo http://orcid.org/0000-0002-8965-1998 Xian-Ke Luo http://orcid.org/0000-0002-4667-7821 Yan-Qiang Huang http://orcid.org/0000-0002-0867-0178 Zan-Song Huang http://orcid.org/0000-0002-0683-2882
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 32060018 National Natural Science Foundation of China 32360035 Through Special Fund Projects for Guide Local Science and Technology Development by the China Government GUIKEZY20198004 Anhui Provincial Natural Science Foundation 2308085QH245 the Natural Science Foundation of the Anhui Higher Education Institutions of China 2023AH040261 Changzhou Science and Technology Project Fund CJ20210012
Corresponding Author	Zan-Song Huang, N/A, Professor, Guangxi Technology Innovation Cooperation Base of Prevention and Control Pathogenic Microbes with Drug Resistance, Youjiang Medical University for Nationalities, No. 98 Urban-Rural Road, Baise 533000, Guangxi Zhuang Autonomous Region, China. 1019846481@qq.com
Key Words	Helicobacter pylori; Sodium selenite; Virulence factors; Adherence; Inflammation
Core Tip	The situation caused by Helicobacter pylori (H. pylori) drug resistance is critical. Selenium is one of the trace elements in the human body, and its content in the stomach is related to the degree of H. pylori infection. Initial studies found that sodium selenite had an inhibitory effect on H. pylori, so we further investigated the mechanism of action of sodium selenite on H. pylori. This study provides an experimental basis for use of the trace element selenium in the treatment of H. pylori infection.
Publish Date	2024-01-06 12:15
Citation	Qin C, Huang GR, Guan AX, Zhou WT, Chen H, Luo PP, Luo XK, Huang YQ, Huang ZS. Mechanistic research: Selenium regulates virulence factors, reducing adhesion ability and inflammatory damage of Helicobacter pylori. World J Gastroenterol 2024; 30(1): 91-107
URL	https://www.wjgnet.com/1007-9327/full/v30/i1/91.htm
DOI	https://dx.doi.org/10.3748/wjg.v30.i1.91

Full Article (PDF)	WJG-30-91-with-cover.pdf
Full Article (Word)	WJG-30-91.docx
The ARRIVE Guidelines	87853-The ARRIVE guidelines.pdf
Manuscript File	87853-Review-Filipodia.docx
Answering Reviewers	87853-Answering reviewers.pdf
Audio Core Tip	87853-Audio core tip.mp3
Biostatistics Review Certificate	87853-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	87853-Conflict-of-interest statement.pdf
Copyright License Agreement	87853-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	87853-Grant application form(s).pdf
Institutional Animal Care and Use Committee Approval Form or Document	87853-Institutional animal care and use committee statement.pdf
Non-Native Speakers of English Editing Certificate	87853-Language certificate.pdf
Supplementary Material	87853-Supplementary material.pdf
Peer-review Report	87853-Peer-review(s).pdf
Scientific Misconduct Check	87853-Bing-Lin C-2.png
Scientific Editor Work List	87853-Scientific editor work list.pdf
CrossCheck Report	87853-CrossCheck.png
CrossCheck Report	87853-CrossCheck report.pdf