Publication Name	World Journal of Clinical Oncology
Manuscript ID	8801
Country	United States

Received	2014-01-08 10:16
Peer-Review Started	2014-01-09 09:53
To Make the First Decision	2014-02-27 09:57
Return for Revision	2014-03-10 20:31
Revised	2014-04-02 01:57
Second Decision	2014-05-29 16:49
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-05-29 17:09
Articles in Press	2014-05-29 17:19
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-07-21 16:09
Publish the Manuscript Online	2014-08-01 15:17

ISSN	2218-4333 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Topic Highlights
Article Title	Targeting autophagy in breast cancer
Manuscript Source	Invited Manuscript
All Author List	Paola Maycotte and Andrew Thorburn
Funding Agency and Grant Number	Funding Agency Grant Number NIH CA150925 Cancer League of Colorado, Inc. to PM, in part
Corresponding Author	Andrew Thorburn, Professor and Chair, Department of Pharmacology, University of Colorado School of Medicine, Mail Stop 8303, 12801 East 17th Avenue, Aurora, CO 80045, United States. andrew.thorburn@ucdenver.edu
Key Words	Autophagy; Cancer; Breast cancer; Chemotherapy; Radiation; Estrogen receptor; HER2; Triple negative breast cancer
Core Tip	Autophagy is thought to be a tumor suppressor pathway. However, once a tumor is formed, it may contribute to tumor cell survival in response to metabolic stress or to therapy. On the other hand, it has also been suggested that autophagy could be induced during breast cancer therapy to kill cells that avoid apoptosis. Here, we discuss some of the recent findings relating autophagy and cancer with a particular focus on breast cancer therapy. We conclude that there are important unresolved questions that should be addressed before autophagy can be successfully targeted for breast cancer treatment.
Publish Date	2014-08-01 15:17
Citation	Maycotte P, Thorburn A. Targeting autophagy in breast cancer. World J Clin Oncol 2014; 5(3): 224-240
URL	http://www.wjgnet.com/2218-4333/full/v5/i3/224.htm
DOI	http://dx.doi.org/10.5306/wjco.v5.i3.224

Full Article (PDF)	WJCO-5-224.pdf
Full Article (Word)	WJCO-5-224.doc
Manuscript File	8801-Review.docx
Answering Reviewers	8801-Answering reviewers.pdf
Copyright License Agreement	8801-Copyright assignment.pdf
Peer-review Report	8801-Peer review(s).pdf
Scientific Misconduct Check	8801-CrossCheck.jpg
Scientific Editor Work List	8801-Scientific editor work list.pdf