Publication Name	World Journal of Cardiology
Manuscript ID	88032
Country	China

Received	2023-09-06 15:47
Peer-Review Started	2023-09-06 15:48
To Make the First Decision
Return for Revision	2023-09-20 07:16
Revised	2023-09-27 03:17
Second Decision	2023-10-18 00:15
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2023-10-27 09:12
Articles in Press	2023-10-27 09:12
Publication Fee Transferred
Edit the Manuscript by Language Editor	2023-10-17 03:22
Typeset the Manuscript	2023-11-20 06:18
Publish the Manuscript Online	2023-11-23 08:41

ISSN	1949-8462 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Cardiac & Cardiovascular Systems
Manuscript Type	Case Report
Article Title	Down syndrome child with multiple heart diseases: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Mo-Wei Kong, Yi-Jing Li, Jun Li, Zhen-Ying Pei, Yu-Yu Xie and Guo-Xiang He
ORCID	Author(s) ORCID Number Mo-Wei Kong http://orcid.org/0000-0002-1214-164X Jun Li http://orcid.org/0009-0003-1481-9914 Guo-Xiang He http://orcid.org/0009-0005-2285-6947
Funding Agency and Grant Number
Corresponding Author	Jun Li, MD, Doctor, Department of Cardiology, Guiqian International General Hospital, No. 1 Dongfeng Avenue, Wudang Distract, Guiyang 550018, Guizhou Province, China. 492847537@qq.com
Key Words	Down syndrome; Trisomy 21 syndrome; Atrial septal defect; Pulmonary hypertension; Review; Patent ductus arteriosus; Case report
Core Tip	This case study presents a 13-year-old boy diagnosed with Down syndrome alongside atrial septal defect, patent ductus arteriosus, and severe pulmonary hypertension. A complex condition initially met with surgical treatment denial due to high risks, highlights the significant challenges faced by individuals with Down syndrome and congenital heart disease. The importance of timely intervention, a multidisciplinary approach, and continued research are highlighted, with a focus to improve prognosis, life expectancy, and understanding of these intricate conditions.
Publish Date	2023-11-23 08:41
Citation	Kong MW, Li YJ, Li J, Pei ZY, Xie YY, He GX. Down syndrome child with multiple heart diseases: A case report. World J Cardiol 2023; 15(11): 615-622
URL	https://www.wjgnet.com/1949-8462/full/v15/i11/615.htm
DOI	https://dx.doi.org/10.4330/wjc.v15.i11.615

Full Article (PDF)	WJC-15-615-with-cover.pdf
Full Article (Word)	WJC-15-615.docx
CARE Checklist–2016	88032-CARE Checklist (2016).PDF
Manuscript File	88032_Auto_Edited-CL-WangTQ-JLW.docx
Answering Reviewers	88032-Answering reviewers.pdf
Audio Core Tip	88032-Audio core tip.wav
Conflict-of-Interest Disclosure Form	88032-Conflict-of-interest statement.pdf
Copyright License Agreement	88032-Copyright license agreement.pdf
Signed Consent for Treatment Form(s) or Document(s)	88032-Informed consent statement.pdf
Non-Native Speakers of English Editing Certificate	88032-Language certificate.pdf
Peer-review Report	88032-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	88032-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	88032-Bing-Lin C-2.png
Scientific Editor Work List	88032-Scientific editor work list.pdf