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1/12/2024 10:36:11 AM | Browse: 362 | Download: 1235
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Received |
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2023-09-07 14:14 |
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Peer-Review Started |
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2023-09-07 14:15 |
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First Decision by Editorial Office Director |
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2023-11-17 09:10 |
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Return for Revision |
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2023-11-17 09:10 |
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Revised |
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2023-11-27 06:25 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2023-12-18 03:54 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2023-12-25 06:08 |
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Articles in Press |
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2023-12-25 06:08 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2024-01-04 02:40 |
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Publish the Manuscript Online |
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2024-01-12 10:36 |
| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Endocrinology & Metabolism |
| Manuscript Type |
Basic Study |
| Article Title |
Urinary exosomal microRNA-145-5p and microRNA-27a-3p act as noninvasive diagnostic biomarkers for diabetic kidney disease
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Lu-Lu Han, Sheng-Hai Wang, Ming-Yan Yao and Hong Zhou |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Nature Science Foundation of Hebei Province |
H2023104011 |
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| Corresponding Author |
Hong Zhou, PhD, Chief Physician, Doctor, Doctor, Department of Endocrinology, The Second Hospital of Hebei Medical University, No. 215 Heping West Road, Shijiazhuang 050000, Hebei Province, China. zhoubs2013@163.com |
| Key Words |
Urinary exosome; MicroRNA-145-5p; MicroRNA-27a-3p; Diabetic kidney disease; Diagnostic biomarkers |
| Core Tip |
Diabetic kidney disease (DKD) is a serious complication of diabetes mellitus (DM). Novel biomarkers and effective therapeutic targets for DKD are needed in clinical settings. In this study, urinary exosomal microRNA-145-5p (miR-145-5p) and miR-27a-3p from patients with DKD were associated with kidney injury progression in type 2 DM patients. MiR-145-5p was highly specific and sensitive to DKD. It may be involved in the signaling pathways related to the pathological processes of DKD. Urinary exosomal miR-145-5p and miR-27a-3p may serve as novel noninvasive diagnostic biomarkers and therapy targets for DKD. |
| Publish Date |
2024-01-12 10:36 |
| Citation |
Han LL, Wang SH, Yao MY, Zhou H. Urinary exosomal microRNA-145-5p and microRNA-27a-3p act as noninvasive diagnostic biomarkers for diabetic kidney disease. World J Diabetes 2024; 15(1): 92-104 |
| URL |
https://www.wjgnet.com/1948-9358/full/v15/i1/92.htm |
| DOI |
https://dx.doi.org/10.4239/wjd.v15.i1.92 |
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