| ISSN |
2222-0682 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Public, Environmental & Occupational Health |
| Manuscript Type |
Observational Study |
| Article Title |
Inflammatory bowel disease among first generation immigrants in Israel: A nationwide epi-Israeli Inflammatory Bowel Disease Research Nucleus study
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Mira Stulman, Gili Focht, Yiska Loewenberg Weisband, Shira Greenfeld, Amir Ben Tov, Natan Ledderman, Eran Matz, Ora Paltiel, Shmuel Odes, Iris Dotan, Eric Ian Benchimol and Dan Turner |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Leona M. and Harry B. Helmsley Charitable Trust |
G-2018PG-CD009 |
|
| Corresponding Author |
Dan Turner, The Juliet Keiden Institute of Pediatric Gastroenterology and Nutrition, Shaare Zedek Medical Center, Faculty of Medicine, The Hebrew University of Jerusalem, Shmuel (Hans) Beyth St 12, Jerusalem 9103102, Israel. turnerd@szmc.org.il |
| Key Words |
Epidemiology; Inflammatory bowel disease; Immigration; Environment |
| Core Tip |
In this nationwide study, we compared inflammatory bowel disease (IBD) rates between first-generation immigrants originating from countries of varying IBD risk vs Israel-born residents. Our focus on the Jewish population was aimed at narrowing the genetic variation of IBD that is usually present in immigration cohorts. We found that the prevalence rate was lower among patients from intermediate- and low-risk regions compared to patients from high-risk regions but in both, the prevalence increased in association with duration in Israel after immigration. This finding, especially among immigrants from intermediate- and low-risk countries, lends support toward the role of environmental factors in IBD pathogenesis in Israel. |
| Publish Date |
2023-12-20 14:52 |
| Citation |
Stulman M, Focht G, Loewenberg Weisband Y, Greenfeld S, Ben Tov A, Ledderman N, Matz E, Paltiel O, Odes S, Dotan I, Benchimol EI, Turner D. Inflammatory bowel disease among first generation immigrants in Israel: A nationwide epi-Israeli Inflammatory Bowel Disease Research Nucleus study. World J Methodol 2023; 13(5): 475-483 |
| URL |
https://www.wjgnet.com/2222-0682/full/v13/i5/475.htm |
| DOI |
https://dx.doi.org/10.5662/wjm.v13.i5.475 |
