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11/10/2014 7:09:00 PM | Browse: 1015 | Download: 1025
Publication Name World Journal of Gastroenterology
Manuscript ID 8818
Country China
Received
2014-01-08 13:52
Peer-Review Started
2014-01-08 21:40
To Make the First Decision
2014-03-13 19:00
Return for Revision
2014-03-20 09:15
Revised
Second Decision
2014-07-22 16:48
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-07-22 17:05
Articles in Press
2014-07-22 18:27
Publication Fee Transferred
Edit the Manuscript by Language Editor
2014-08-30 02:55
Typeset the Manuscript
2014-10-25 21:48
Publish the Manuscript Online
2014-11-10 19:10
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Autobiography
Article Title Resveratrol and genistein inhibition of rat isolated gastrointestinal contractions and related mechanisms
Manuscript Source Unsolicited Manuscript
All Author List Li-Xue Zhang, Hong-Fang Li, Long-De Wang, Shan Jin, Xing-Cheng Dou, Zhi-Feng Tian and Qin Ma
Funding Agency and Grant Number
Funding Agency Grant Number
Administration of Lanzhou Scientific Technology 2010-1-88
Gansu Natural Science Fund in China 1010RJZA111
National Natural Science Foundation of China 21272103
National Natural Science Foundation of China 81360540
Corresponding Author Hong-Fang Li, Professor, Key Laboratory of Pre-clinical Study for New Drugs of Gansu Province, Department of Physiology, College of Basic Medicine, Lanzhou University, 199 Donggang West Road, Lanzhou 730000, Gansu Province, China. lihf@lzu.edu.cn
Key Words Ca2+ channel; Gastrointestinal; Motility; Phytoestrogen; Smooth muscle
Core Tip Female hormones can cause gastrointestinal motility disorder and may contribute to irritable bowel syndrome. As analogs of estrogen, the phytoestrogens resveratrol and genistein possess variable degrees of agonistic/antagonistic effects, but little is known about their effects on gastrointestinal motility. The present study demonstrates that, similar to estrogen, resveratrol and genistein attenuate gastrointestinal smooth muscle motility through various mechanisms. The results reflect the physiologic and pharmacologic actions of resveratrol and genistein, provide the pharmacologic guidance for the application of these compounds, and are also very valuable for medicine and nutrition.
Publish Date 2014-11-10 19:10
Citation Zhang LX, Li HF, Wang LD, Jin S, Dou XC, Tian ZF, Ma Q. Resveratrol and genistein inhibition of rat isolated gastrointestinal contractions and related mechanisms. World J Gastroenterol 2014; 20(41): 15335-15342
URL http://www.wjgnet.com/1007-9327/full/v20/i41/15335.htm
DOI http://dx.doi.org/10.3748/wjg.v20.i41.15335
Full Article (PDF) WJG-20-15335.pdf
Full Article (Word) WJG-20-15335.doc
Manuscript File 8818-Review.doc
Answering Reviewers 8818-Answering reviewers.pdf
Copyright License Agreement 8818-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate 8818-Language certificate.pdf
Peer-review Report 8818-Peer review(s).pdf
Scientific Misconduct Check 8818-CrossCheck.jpg
Scientific Editor Work List 8818-Scientific editor work list.pdf