Publication Name	World Journal of Clinical Cases
Manuscript ID	88186
Country	Greece

Received	2023-09-14 09:22
Peer-Review Started	2023-09-13 17:16
To Make the First Decision
Return for Revision	2023-12-05 02:15
Revised	2023-12-05 08:15
Second Decision	2023-12-12 03:02
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2023-12-12 06:29
Articles in Press	2023-12-12 06:29
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2023-12-15 09:33
Publish the Manuscript Online	2023-12-22 08:49

ISSN	2307-8960 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Cardiac & Cardiovascular Systems
Manuscript Type	Letter to the Editor
Article Title	Lyophilized recombinant human brain natriuretic peptide: A promising therapy in patients with chronic heart failure
Manuscript Source	Invited Manuscript
All Author List	Christos Kourek, Alexandros Briasoulis, Grigorios Giamouzis, John Skoularigis and Andrew Xanthopoulos
ORCID	Author(s) ORCID Number Christos Kourek http://orcid.org/0000-0003-4348-2153 Alexandros Briasoulis http://orcid.org/0000-0002-5740-9670 Grigorios Giamouzis http://orcid.org/0000-0002-7406-5427 John Skoularigis http://orcid.org/0000-0001-7159-2478 Andrew Xanthopoulos http://orcid.org/0000-0002-9439-3946
Funding Agency and Grant Number
Corresponding Author	Andrew Xanthopoulos, FACC, MD, PhD, Senior Postdoctoral Fellow, Department of Cardiology, University Hospital of Larissa, Mezourlo, Larissa 41110, Greece. andrewvxanth@gmail.com
Key Words	Heart failure; Recombinant; Brain natriuretic peptide; Outcomes
Core Tip	Lyophilized recombinant brain natriuretic peptide is an exogenous peptide synthesized by artificial recombination technology, with a similar structure and similar physiological effects with the endogenous natriuretic peptide secreted by the human body. A recent single center, randomized study examined its safety and efficacy in 102 chronic heart failure patients, showing promising results. Larger randomized controlled trials are urgently needed.
Publish Date	2023-12-22 08:49
Citation	Kourek C, Briasoulis A, Giamouzis G, Skoularigis J, Xanthopoulos A. Lyophilized recombinant human brain natriuretic peptide: A promising therapy in patients with chronic heart failure. World J Clin Cases 2023; 11(36): 8603-8605
URL	https://www.wjgnet.com/2307-8960/full/v11/i36/8603.htm
DOI	https://dx.doi.org/10.12998/wjcc.v11.i36.8603

Full Article (PDF)	WJCC-11-8603-with-cover.pdf
Full Article (Word)	WJCC-11-8603.docx
Manuscript File	88186_Auto_Edited-YJP.docx
Answering Reviewers	88186-Answering reviewers.pdf
Audio Core Tip	88186-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	88186-Conflict-of-interest statement.pdf
Copyright License Agreement	88186-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	88186-Language certificate.pdf
Peer-review Report	88186-Peer-review(s).pdf
Scientific Misconduct Check	88186-Bing-Qu XL-2.jpg
Scientific Editor Work List	88186-Scientific editor work list.pdf
CrossCheck Report	88186-CrossCheck report.pdf