Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	8823
Country	United Kingdom

Received	2014-01-20 17:40
Peer-Review Started	2014-01-21 09:38
To Make the First Decision	2014-02-13 16:02
Return for Revision	2014-02-20 20:43
Revised	2014-03-13 19:34
Second Decision	2014-04-11 18:47
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-04-11 19:07
Articles in Press	2014-05-23 12:19
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-06-13 13:59
Publish the Manuscript Online	2014-06-20 15:55

ISSN	1948-5204 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Review
Article Title	Operable gastro-oesophageal junctional adenocarcinoma: Where to next?
Manuscript Source	Invited Manuscript
All Author List	Elizabeth C Smyth and David Cunningham
Funding Agency and Grant Number	Funding Agency Grant Number NIHR RM/ICR Biomedical Research Centre
Corresponding Author	Dr. Elizabeth Smyth, Department of Gastrointestinal Oncology, Royal Marsden Hospital, Downs Road, Sutton SM2 5PT, United Kingdom. elizabeth.smyth@rmh.nhs.uk
Key Words	Oesophageal adenocarcinoma; Junctional adenocarcinoma; Gastric adenocarcinoma; Peri-operative chemotherapy; Pre-operative chemoradiotherapy; Molecular profiling; Fluoro-deoxyglucose-positron emission tomography; Barrett’s oesophagus; Chemoprevention
Core Tip	Cancer of the gastro-oesophageal junction is an increasingly common phenomenon. For patients with operable junctional cancer, the only curative treatment option is surgery, however the optimal peri-operative treatment is controversial. We review the evidence supporting the use of chemotherapy and chemoradiotherapy in the pre- and postoperative settings for these patients, and go on to highlight how current research into the molecular mechanisms underpinning gastro-oesophageal cancer may lead to future effective treatment options.
Publish Date	2014-06-20 15:55
Citation	Smyth EC, Cunningham D. Operable gastro-oesophageal junctional adenocarcinoma: Where to next? World J Gastrointest Oncol 2014; 6(6): 145-155
URL	http://www.wjgnet.com/1948-5204/full/v6/i6/145.htm
DOI	http://dx.doi.org/10.4251/wjgo.v6.i6.145

Full Article (PDF)	WJGO-6-145.pdf
Full Article (Word)	WJGO-6-145.doc
Manuscript File	8823-Review.docx
Answering Reviewers	8823-Answering reviewers.pdf
Copyright License Agreement	8823-Copyright assignment.pdf
Peer-review Report	8823-Peer review(s).pdf
Scientific Editor Work List	8823-Scientific editor work list.doc