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Articles Published Processes
8/22/2014 2:48:00 PM | Browse: 1085 | Download: 1020
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Received |
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2014-01-20 17:43 |
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Peer-Review Started |
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2014-01-21 09:48 |
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To Make the First Decision |
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2014-02-13 16:02 |
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Return for Revision |
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2014-02-20 20:43 |
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Revised |
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2014-02-27 04:57 |
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Second Decision |
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2014-03-14 18:22 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2014-03-14 18:36 |
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Articles in Press |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2014-05-28 09:30 |
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Publish the Manuscript Online |
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2014-06-20 19:33 |
Category |
Cardiac & Cardiovascular Systems |
Manuscript Type |
Review |
Article Title |
Alterations in cell adhesion proteins and cardiomyopathy
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Manuscript Source |
Invited Manuscript |
All Author List |
Jifen Li |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
American Heart Association Scientist Development |
N2080068 |
W.W. Smith Charitable Trust Foundation |
H1204 |
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Corresponding Author |
Jifen Li, MD, PhD, Center for Translational Medicine, Department of Medicine, Jefferson Medical College, Thomas Jefferson University, Jeff Alumni Hall Suite 543, 1020 Locus St., Philadelphia, PA 19107, United States. jifen.li@jefferson.edu |
Key Words |
Cardiomyopathy; Adherens junction; Desmosome; Intercalated disc; Arrhythmia |
Core Tip |
Cell adhesive junction is a specialized intercellular structure in the heart, and essential to maintain heart contractile function. Alterations in adhesive proteins have been found to lead to various forms of cardiomyopathy. However, the molecular and cellular mechanisms underlying heart muscle dysfunction caused by those cell adhesive molecules have not been completely understood. This review provides most recent development on cellular composition of the cell adhesion proteins and their related gene mutations, disease phenotypes, potential mechanisms involved in cardiomyopathies. |
Publish Date |
2014-06-20 19:33 |
Citation |
Li J. Alterations in cell adhesion proteins and cardiomyopathy. World J Cardiol 2014; 6(5): 304-313 |
URL |
http://www.wjgnet.com/1949-8462/full/v6/i5/304.htm |
DOI |
http://dx.doi.org/10.4330/wjc.v6.i5.304 |
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