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Articles Published Processes
12/25/2023 6:03:15 AM | Browse: 271 | Download: 1562
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Received |
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2023-09-20 10:05 |
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Peer-Review Started |
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2023-09-20 10:07 |
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First Decision by Editorial Office Director |
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2023-10-25 13:28 |
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Return for Revision |
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2023-10-25 13:28 |
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Revised |
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2023-11-03 06:29 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2023-11-14 02:06 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2023-11-21 07:33 |
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Articles in Press |
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2023-11-21 07:33 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2023-11-27 00:36 |
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Publish the Manuscript Online |
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2023-12-25 06:03 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Virology |
| Manuscript Type |
Observational Study |
| Article Title |
Serum omentin-1 is correlated with the severity of liver disease in patients with chronic hepatitis C
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Georg Peschel, Kilian Weigand, Jonathan Grimm, Martina Müller and Christa Buechler |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Christa Buechler, PhD, Senior Researcher, Department of Internal Medicine I, University Hospital Regensburg, Franz-Josef-Strauss Allee 11, Regensburg 93053, Germany. christa.buechler@klinik.uni-regensburg.de |
| Key Words |
Direct acting antivirals; Hepatitis C; Liver cirrhosis; Adipokine |
| Core Tip |
Omentin-1 is an adipokine well described for its anti-inflammatory and insulin-sensitizing functions. Aim of this study was to identify the effect of hepatitis C virus (HCV) infection and liver cirrhosis on serum omentin-1 levels. This study showed that circulating omentin-1 levels of HCV infected patients and non-infected healthy controls were similar. Accordingly, serum omentin-1 levels did not change upon effective elimination of the virus by direct acting antiviral therapy. Serum omentin-1 was not associated with diabetes or C-reactive protein in the HCV cohort. Patients with liver cirrhosis had increased serum omentin-1 levels before treatment and at sustained virological response 12 in comparison to HCV patients without liver cirrhosis. This analysis shows that increased serum omentin-1 levels of chronic HCV patients with liver cirrhosis persists after viral elimination. Serum omentin-1 has no role in the favourable metabolic outcomes of HCV eradication. |
| Publish Date |
2023-12-25 06:03 |
| Citation |
Peschel G, Weigand K, Grimm J, Müller M, Buechler C. Serum omentin-1 is correlated with the severity of liver disease in patients with chronic hepatitis C. World J Hepatol 2023; 15(12): 1315-1324 |
| URL |
https://www.wjgnet.com/1948-5182/full/v15/i12/1315.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v15.i12.1315 |
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