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Articles Published Processes
2/4/2024 10:57:42 AM | Browse: 217 | Download: 678
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Received |
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2023-09-21 14:57 |
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Peer-Review Started |
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2023-09-21 14:58 |
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To Make the First Decision |
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Return for Revision |
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2023-11-09 04:01 |
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Revised |
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2023-11-21 06:45 |
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Second Decision |
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2023-12-20 10:34 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2023-12-27 05:38 |
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Articles in Press |
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2023-12-27 05:38 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2024-01-29 16:54 |
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Publish the Manuscript Online |
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2024-02-04 10:57 |
| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Medical Informatics |
| Manuscript Type |
Clinical and Translational Research |
| Article Title |
Identification of hub genes associated with Helicobacter pylori infection and type 2 diabetes mellitus: A pilot bioinformatics study
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Han Chen, Guo-Xin Zhang and Xiao-Ying Zhou |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
82100594 |
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| Corresponding Author |
Xiao-Ying Zhou, MD, PhD, Associate Chief Physician, Department of Gastroenterology, Jiangsu Province Hospital, No. 300 Guangzhou Road, Nanjing 210029, Jiangsu Province, China. zhouxiaoying0926@njmu.edu.cn |
| Key Words |
Helicobacter pylori; Type 2 diabetes mellitus; Bioinformatics analysis; Differentially expressed genes; Hub genes |
| Core Tip |
This bioinformatic research is the one of the first studies to identify the key genes and pathways associated with both Helicobacter pylori (H. pylori) infection and type 2 diabetes mellitus (T2DM), using integrated bioinformatics analyses. Five hub genes were identified, including TLR4, C5AR1, ITGAM, FCGR2A, FCER1G, and all of which were closely related to immune cell infiltration. We also verified their expression in clinical specimens. Hopefully, this study will shed some light on the pathogenesis of H. pylori-induced T2DM in the future. This study is of great clinical importance. |
| Publish Date |
2024-02-04 10:57 |
| Citation |
Chen H, Zhang GX, Zhou XY. Identification of hub genes associated with Helicobacter pylori infection and type 2 diabetes mellitus: A pilot bioinformatics study. World J Diabetes 2024; 15(2): 170-185 |
| URL |
https://www.wjgnet.com/1948-9358/full/v15/i2/170.htm |
| DOI |
https://dx.doi.org/10.4239/wjd.v15.i2.170 |
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