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Articles Published Processes
7/12/2024 3:55:59 PM | Browse: 128 | Download: 366
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Received |
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2023-09-27 11:18 |
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Peer-Review Started |
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2023-09-27 11:20 |
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First Decision by Editorial Office Director |
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2023-12-07 00:14 |
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Return for Revision |
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2023-12-07 00:38 |
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Revised |
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2024-02-22 00:23 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2024-03-20 02:36 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2024-03-20 04:57 |
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Articles in Press |
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2024-03-20 04:57 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2024-05-22 07:17 |
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Publish the Manuscript Online |
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2024-07-12 15:55 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Immunology |
| Manuscript Type |
Basic Study |
| Article Title |
Kombo knife combined with sorafenib in liver cancer treatment: Efficacy and safety under immune function influence
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yang Cao, Pei-Pei Li, Bing-Li Qiao and Quan-Wang Li |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Henan Province Medical Science and Technology Tackling Program Joint Co-Construction Project |
LHGJ20191024 |
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| Corresponding Author |
Pei-Pei Li, MM, Attending Doctor, Department of Oncology, The Third People's Hospital of Zhengzhou, No. 136 Nanshuncheng Street, Guancheng District, Zhengzhou 450000, Henan Province, China. Lpp20210224@126.com |
| Key Words |
Immune infiltration; Prognostic genes; Sorafenib; Kombo knife; The cancer genome atlas analysis; Hepatocellular carcinoma |
| Core Tip |
In this groundbreaking study, we explore the synergistic effects of Kombo Knife and sorafenib in hepatocellular carcinoma (HCC) treatment, utilizing insights from the cancer genome atlas. Employing advanced data analytics, including weighted gene coexpression network analysis and machine learning, we identify key immune genes-particularly peptidylprolyl isomerase A and solute carrier family 29 member 3-as significant prognostic markers. Our findings highlight the enhanced therapeutic efficacy of the combined regimen, marked by improved progression-free survival and response rates. This research represents a significant stride in HCC therapy, pivoting towards innovative, immune-centric treatment strategies that promise to transform patient outcomes. |
| Publish Date |
2024-07-12 15:55 |
| Citation |
Cao Y, Li PP, Qiao BL, Li QW. Kombo knife combined with sorafenib in liver cancer treatment: Efficacy and safety under immune function influence. World J Gastrointest Oncol 2024; 16(7): 3118-3157 |
| URL |
https://www.wjgnet.com/1948-5204/full/v16/i7/3118.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v16.i7.3118 |
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