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12/6/2023 8:08:50 AM | Browse: 92 | Download: 151
Publication Name World Journal of Clinical Cases
Manuscript ID 88559
Country China
Received
2023-10-03 14:29
Peer-Review Started
2023-10-03 14:31
To Make the First Decision
Return for Revision
2023-11-01 03:02
Revised
2023-11-11 11:09
Second Decision
2023-11-20 01:40
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2023-11-27 07:19
Articles in Press
2023-11-27 07:19
Publication Fee Transferred
Edit the Manuscript by Language Editor
2023-11-19 09:48
Typeset the Manuscript
2023-11-30 09:07
Publish the Manuscript Online
2023-12-06 08:08
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Hematology
Manuscript Type Case Report
Article Title Hemophagocytic lymphohistiocytosis with jaundice as first manifestation: A case report
Manuscript Source Unsolicited Manuscript
All Author List Dan-Dan Wang, Sheng Wu, Bing-Bing Kong and Lin-Lin Song
ORCID
Author(s) ORCID Number
Dan-Dan Wang http://orcid.org/0009-0008-2356-928X
Sheng Wu http://orcid.org/0000-0003-0362-9894
Bing-Bing Kong http://orcid.org/0009-0007-6762-436X
Lin-Lin Song http://orcid.org/0000-0001-6398-6725
Funding Agency and Grant Number
Corresponding Author Lin-Lin Song, PhD, Chief Physician, Doctor, Department of Emergency Medicine, Beijing Tsinghua Changgung Hospital, Medical Center, Tsinghua University, No. 168 Litang Road, Changping District, Beijing 102218, China. slla01139@btch.edu.cn
Key Words Hemophagocytic lymphohistiocytosis; Jaundice; Common bile duct stones; Bile duct obstruction; Septic shock; Case report
Core Tip We report the case of a 71-year-old female patient who presented with jaundice. Obstructive jaundice with choledocholithiasis and gallstones was suggested. Then, we found splenomegaly, cytopenia, hypertriglyceridemia, hypofibrinogenemia, and elevated ferritin. Bone marrow biopsy revealed hemophagocytosis. Later, cardiac arrest occurred when she returned after the surgery. We considered that hemophagocytic lymphohistiocytosis (HLH) was triggered by septic shock. The patient’s condition deteriorated rapidly, with multiple organ dysfunction. Corticosteroid therapy and symptomatic treatment failed to save her life. Jaundice rarely presents as the first symptom in HLH patients. Elevated direct bilirubin was associated with prognosis. Clinicians should try to reduce missed diagnoses and misdiagnoses.
Publish Date 2023-12-06 08:08
Citation Wang DD, Wu S, Kong BB, Song LL. Hemophagocytic lymphohistiocytosis with jaundice as first manifestation: A case report. World J Clin Cases 2023; 11(34): 8212-8218
URL https://www.wjgnet.com/2307-8960/full/v11/i34/8212.htm
DOI https://dx.doi.org/10.12998/wjcc.v11.i34.8212
Full Article (PDF) WJCC-11-8212-with-cover.pdf
Full Article (Word) WJCC-11-8212.docx
CARE Checklist–2016 88559-CARE Checklist (2016).pdf
Manuscript File 88559_Auto_Edited-CL-WangTQ-JLW.docx
Answering Reviewers 88559-Answering reviewers.pdf
Audio Core Tip 88559-Audio core tip.wav
Conflict-of-Interest Disclosure Form 88559-Conflict-of-interest statement.pdf
Copyright License Agreement 88559-Copyright license agreement.pdf
Signed Consent for Treatment Form(s) or Document(s) 88559-Informed consent statement.pdf
Non-Native Speakers of English Editing Certificate 88559-Language certificate.pdf
Peer-review Report 88559-Peer-review(s).pdf
Scientific Misconduct Check 88559-Bing-Lin C-2.png
Scientific Editor Work List 88559-Scientific editor work list.pdf