Publication Name	World Journal of Transplantation
Manuscript ID	8862
Country	United States

Received	2014-01-09 11:23
Peer-Review Started	2014-01-09 22:03
To Make the First Decision	2014-03-12 16:47
Return for Revision	2014-03-20 20:25
Revised	2014-07-08 00:00
Second Decision	2014-07-18 13:47
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-07-18 13:57
Articles in Press	2014-07-18 13:57
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-10-22 17:10
Publish the Manuscript Online	2014-10-24 17:01

ISSN	2220-3230 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Transplantation
Manuscript Type	Retrospective Study
Article Title	D-MELD risk capping improves post-transplant and overall mortality under markov microsimulation
Manuscript Source	Unsolicited Manuscript
All Author List	Jeffrey B Halldorson, Robert L Carithers Jr, Renuka Bhattacharya, Ramasamy Bakthavatsalam, Iris W Liou, Andre A Dick, Jorge D Reyes and James D Perkins
Funding Agency and Grant Number
Corresponding Author	Jeffrey B Halldorson, MD, Division of Transplant Surgery, Department of Surgery, University of California, Suite 2-286, 200 West Arbor Drive, #8401, San Diego, CA 92103-8401, United States. jhalldorson@ucsd.edu
Key Words	Liver transplantation; The product of calculated Model for End-Stage Liver Disease score excluding exception points and donor age; Donor/recipient matching; Markov microsimulation; Model for End-Stage Liver Disease; Donor age
Core Tip	Optimal matching between donor livers and recipients balances recipient need with optimal utility. The product of calculated Model for End-Stage Liver Disease score excluding exception points and donor age (D-MELD) risk cap uniquely utilizes ethically neutral donor/recipient factors while maintaining predictive power, making it useful for donor/recipient matching paradigms aimed at improving utility. Described is a novel utilization of the D-MELD risk cap as an aid for donor/recipient matching. Markov modeling suggests that this paradigm improves outcomes both by decreasing futile transplantations but also by focusing the majority of transplantation on moderate Model for End-Stage Liver Disease (MELD) recipients while continuing to provide younger donor livers for the fewer number of patients transplanted at high MELD.
Publish Date	2014-10-24 17:01
Citation	Halldorson JB, Carithers Jr RL, Bhattacharya R, Bakthavatsalam R, Liou IW, Dick AA, Reyes JD, Perkins JD. D-MELD risk capping improves post-transplant and overall mortality under markov microsimulation. World J Transplant 2014; 4(3): 206-215
URL	http://www.wjgnet.com/2220-3230/full/v4/i3/206.htm
DOI	http://dx.doi.org/10.5500/wjt.v4.i3.206

Full Article (PDF)	WJT-4-206.pdf
Full Article (Word)	WJT-4-206.doc
Manuscript File	8862-Review.doc
Answering Reviewers	8862-Answering reviewers.pdf
Copyright License Agreement	8862-Copyright assignment.pdf
Peer-review Report	8862-Peer review(s).pdf
Scientific Misconduct Check	8862-CrossCheck.jpg
Scientific Editor Work List	8862-Scientific editor work list.pdf