Publication Name	World Journal of Gastroenterology
Manuscript ID	8871
Country	China

Received	2014-01-11 11:59
Peer-Review Started	2014-01-11 16:36
To Make the First Decision	2014-02-26 15:33
Return for Revision	2014-03-11 10:45
Revised
Second Decision	2014-04-23 09:25
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-04-23 10:19
Articles in Press	2014-05-23 10:46
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-05-12 10:21
Typeset the Manuscript	2014-06-09 08:32
Publish the Manuscript Online	2014-06-21 13:56

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Transplantation
Manuscript Type	Autobiography
Article Title	Protective effect of bone marrow mesenchymal stem cells in intestinal barrier permeability after heterotopic intestinal transplantation
Manuscript Source	Unsolicited Manuscript
All Author List	Wen Zhang, Zhong-Yang Shen, Hong-Li Song, Yang Yang, Ben-Juan Wu, Nan-Nan Fu and Tao Liu
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 81270528 Natural Science Foundation of Tianjin, China 08JCYBJC08400 Natural Science Foundation of Tianjin, China 11JCZDJC27800 Natural Science Foundation of Tianjin, China 12JCZDJC25200 Technology Foundation of Health Bureau of Tianjin, China 2011KY11
Corresponding Author	Hong-Li Song, MD, PhD, Professor of Medicine, Department of Organ Transplantation, Tianjin First Central Hospital, No. 24 Fukang Road, Nankai District, Tianjin 300192, China. hlsong26@163.com
Key Words	Bone marrow mesenchymal stem cells; Small intestinal transplantation; Intestinal mucosal barrier; Occludin; Zona occludens-1
Core Tip	Rejection and sepsis after small intestinal transplantation (SITx) is a serious and common complication. The small intestinal mucosal barrier plays an important role in the progression of postoperative complications. This study demonstrated that in rats, implantation of recipient-derived bone marrow mesenchymal stem cells decreased intestinal permeability and preserved intestinal mucosal barrier function after SITx via a mechanism linked to the balance between graft inflammatory cytokine levels and increased expression of the intestinal tight junction proteins occludin and zona occludens-1.
Publish Date	2014-06-21 13:56
Citation	Zhang W, Shen ZY, Song HL, Yang Y, Wu BJ, Fu NN, Liu T. Protective effect of bone marrow mesenchymal stem cells in intestinal barrier permeability after heterotopic intestinal transplantation. World J Gastroenterol 2014; 20(23): 7442-7451
URL	http://www.wjgnet.com/1007-9327/full/v20/i23/7442.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i23.7442

Full Article (PDF)	WJG-20-7442.pdf
Full Article (Word)	WJG-20-7442.doc
Manuscript File	8871-Review.doc
Answering Reviewers	8871-Answering reviewers.pdf
Copyright License Agreement	8871-Copyright assignment.pdf
Peer-review Report	8871-Peer reviews.pdf
Scientific Editor Work List	8871-Scientific editor work list.doc