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Articles Published Processes
11/27/2023 5:08:21 PM | Browse: 257 | Download: 991
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Received |
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2023-10-08 02:53 |
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Peer-Review Started |
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2023-10-08 02:55 |
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To Make the First Decision |
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Return for Revision |
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2023-11-01 01:48 |
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Revised |
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2023-11-06 13:02 |
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Second Decision |
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2023-11-10 09:47 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2023-11-14 08:42 |
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Articles in Press |
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2023-11-14 08:42 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2023-11-22 03:44 |
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Publish the Manuscript Online |
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2023-11-27 17:08 |
ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Clinical and Translational Research |
Article Title |
Causal associations between inflammatory bowel disease and anxiety: A bidirectional Mendelian randomization study
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Ying He, Chun-Lan Chen, Jian He and Si-De Liu |
ORCID |
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Funding Agency and Grant Number |
Funding Agency |
Grant Number |
China Postdoctoral Science Foundation |
No. 2021M701614 |
Guangdong Basic and Applied Basic Research Foundation |
No. 2022A1515111063 and No. 2022A1515111045 |
Foundation of Guangdong Provincial People's Hospital |
No. 8200010545 |
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Corresponding Author |
Si-De Liu, PhD, Professor, Department of Gastroenterology, Nanfang Hospital, Southern Medical University, No. 1838 Guangzhou Avenue North, Guangzhou 510515, Guangdong Province, China. liuside2011@163.com |
Key Words |
Inflammatory bowel disease; Anxiety; Causal effect; Mendelian randomization; Genome-wide association studies |
Core Tip |
Our study provides evidence that genetic susceptibility to ulcerative colitis (UC) is associated with an increased risk of anxiety [odds ratio: 1.071 (95% confidence interval: 1.009, 1.135), P = 0.023], while genetic susceptibility to Crohn’s disease (CD) is not associated with an increased risk of anxiety. No causal effects of anxiety on UC and CD were observed in this study. In conclusion, our study demonstrates the causal effect of UC on anxiety. These findings may be helpful to increase physicians’ awareness of the need to recognize anxiety in UC patients and influence the management of anxiety in clinical practice. |
Publish Date |
2023-11-27 17:08 |
Citation |
He Y, Chen CL, He J, Liu SD. Causal associations between inflammatory bowel disease and anxiety: A bidirectional Mendelian randomization study. World J Gastroenterol 2023; 29(44): 5872-5881 |
URL |
https://www.wjgnet.com/1007-9327/full/v29/i44/5872.htm |
DOI |
https://dx.doi.org/10.3748/wjg.v29.i44.5872 |
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