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Articles Published Processes
10/20/2014 6:36:00 PM | Browse: 1613 | Download: 1935
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Received |
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2014-01-11 12:15 |
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Peer-Review Started |
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2014-01-11 15:11 |
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To Make the First Decision |
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2014-01-24 11:26 |
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Return for Revision |
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2014-01-26 18:00 |
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Revised |
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2014-02-17 03:00 |
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Second Decision |
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2014-06-17 09:15 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2014-06-17 09:46 |
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Articles in Press |
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2014-06-17 10:09 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2014-10-09 10:02 |
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Publish the Manuscript Online |
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2014-10-20 18:35 |
Category |
Geriatrics & Gerontology |
Manuscript Type |
Topic Highlights |
Article Title |
Nonalcoholic fatty liver disease and aging: Epidemiology to management
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Manuscript Source |
Invited Manuscript |
All Author List |
Marco Bertolotti, Amedeo Lonardo, Chiara Mussi, Enrica Baldelli, Elisa Pellegrini, Stefano Ballestri, Dante Romagnoli and Paola Loria |
Funding Agency and Grant Number |
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Corresponding Author |
Marco Bertolotti
Department of Biomedical, Metabolic and Neural Sciences
Nuovo Ospedale Civile di Modena
Via Giardini, 1355
41126 Modena, Italy
Phone 39 059 396 1802
Fax 39 059 396 1335
Email: marco.bertolotti@unimore.it
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Key Words |
Adipose tissue; Atherosclerosis; Aortic valve sclerosis; Autonomic dysfunction; Arrhythmia; Cirrhosis; Dementia; Falls; Frailty; Hepatocellular carcinoma; Microbiota; Nuclear receptors; Pathogenesis; Sarcopenia; Treatment |
Core Tip |
Nonalcoholic fatty liver disease (NAFLD) is a common disease in the elderly, in whom it follows a more severe course due to worse hepatic and extrahepatic manifestations. The former include nonalcoholic steatohepatitis and hepatocellular carcinoma; the latter include cardiovascular and metabolic complications. The pathophysiology, diagnosis and principles of treatment that are specifically relevant to elderly patients with NAFLD are critically revised here. Based on these findings, we conclude that a more accurate understanding of the molecular mechanisms of geriatric NAFLD will help in identifying the most appropriate diagnostic and therapeutic approach in the individual elderly patient. |
Publish Date |
2014-10-20 18:35 |
Citation |
Bertolotti M, Lonardo A, Mussi C, Baldelli E, Pellegrini E, Ballestri S, Romagnoli D, Loria P. Nonalcoholic fatty liver disease and aging: Epidemiology to management. World J Gastroenterol 2014; 20(39): 14185-14204 |
URL |
http://www.wjgnet.com/1007-9327/full/v20/i39/14185.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v20.i39.14185 |
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