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10/20/2014 6:36:00 PM | Browse: 1613 | Download: 1935
Publication Name World Journal of Gastroenterology
Manuscript ID 8879
Country Italy
Received
2014-01-11 12:15
Peer-Review Started
2014-01-11 15:11
To Make the First Decision
2014-01-24 11:26
Return for Revision
2014-01-26 18:00
Revised
2014-02-17 03:00
Second Decision
2014-06-17 09:15
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2014-06-17 09:46
Articles in Press
2014-06-17 10:09
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2014-10-09 10:02
Publish the Manuscript Online
2014-10-20 18:35
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Geriatrics & Gerontology
Manuscript Type Topic Highlights
Article Title Nonalcoholic fatty liver disease and aging: Epidemiology to management
Manuscript Source Invited Manuscript
All Author List Marco Bertolotti, Amedeo Lonardo, Chiara Mussi, Enrica Baldelli, Elisa Pellegrini, Stefano Ballestri, Dante Romagnoli and Paola Loria
Funding Agency and Grant Number
Corresponding Author Marco Bertolotti Department of Biomedical, Metabolic and Neural Sciences Nuovo Ospedale Civile di Modena Via Giardini, 1355 41126 Modena, Italy Phone 39 059 396 1802 Fax 39 059 396 1335 Email: marco.bertolotti@unimore.it
Key Words Adipose tissue; Atherosclerosis; Aortic valve sclerosis; Autonomic dysfunction; Arrhythmia; Cirrhosis; Dementia; Falls; Frailty; Hepatocellular carcinoma; Microbiota; Nuclear receptors; Pathogenesis; Sarcopenia; Treatment
Core Tip Nonalcoholic fatty liver disease (NAFLD) is a common disease in the elderly, in whom it follows a more severe course due to worse hepatic and extrahepatic manifestations. The former include nonalcoholic steatohepatitis and hepatocellular carcinoma; the latter include cardiovascular and metabolic complications. The pathophysiology, diagnosis and principles of treatment that are specifically relevant to elderly patients with NAFLD are critically revised here. Based on these findings, we conclude that a more accurate understanding of the molecular mechanisms of geriatric NAFLD will help in identifying the most appropriate diagnostic and therapeutic approach in the individual elderly patient.
Publish Date 2014-10-20 18:35
Citation Bertolotti M, Lonardo A, Mussi C, Baldelli E, Pellegrini E, Ballestri S, Romagnoli D, Loria P. Nonalcoholic fatty liver disease and aging: Epidemiology to management. World J Gastroenterol 2014; 20(39): 14185-14204
URL http://www.wjgnet.com/1007-9327/full/v20/i39/14185.htm
DOI http://dx.doi.org/10.3748/wjg.v20.i39.14185
Full Article (PDF) WJG-20-14185.pdf
Full Article (Word) WJG-20-14185.doc
Manuscript File 8879-Review.doc
Answering Reviewers 8879-Answering reviewers.pdf
Copyright License Agreement 8879-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate 8879-Language certificate.pdf
Peer-review Report 8879-Peer reviews.pdf
Scientific Misconduct Check 8879-CrossCheck.jpg
Scientific Editor Work List 8879-Scientific editor work list.pdf