Publication Name	World Journal of Gastroenterology
Manuscript ID	88801
Country	China

Received	2023-10-10 02:35
Peer-Review Started	2023-10-10 02:37
To Make the First Decision
Return for Revision	2023-12-27 01:41
Revised	2024-01-07 13:40
Second Decision	2024-02-25 02:39
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-02-25 04:53
Articles in Press	2024-02-25 04:53
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-03-28 06:47
Publish the Manuscript Online	2024-04-03 07:21

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Basic Study
Article Title	Inhibition of hepatitis B virus via selective apoptosis modulation by Chinese patent medicine Liuweiwuling Tablet
Manuscript Source	Unsolicited Manuscript
All Author List	Fei-Lin Ge, Yan Yang, Lan-Lan Si, Yuan-Hua Li, Meng-Zheng Cao, Jun Wang, Zhao-Fang Bai, Zhi-Gang Ren, Xiao-He Xiao and Yan Liu
ORCID	Author(s) ORCID Number Fei-Lin Ge http://orcid.org/0000-0002-0992-474X Lan-Lan Si http://orcid.org/0000-0003-0222-5169 Jun Wang http://orcid.org/0000-0002-6261-8995 Zhao-Fang Bai http://orcid.org/0000-0002-6208-150X Zhi-Gang Ren http://orcid.org/0000-0003-0798-3444 Xiao-He Xiao http://orcid.org/0000-0002-3719-6575 Yan Liu http://orcid.org/0000-0003-1498-4314
Funding Agency and Grant Number	Funding Agency Grant Number National Key Research and Development Program of China No. 2022YFC2303103 the National Funded Postdoctoral Researcher Program of China No. GZC20232406 Henan Province Traditional Chinese Medicine Science Research Project No. 2023ZY3040 Henan Province Medical Science and Technology Research Plan Joint Construction Project No. LHGJ20230233 the National Natural Science Foundation of China No. 81930110
Corresponding Author	Yan Liu, PhD, N/A, N/A, . liuyan5360@163.com
Key Words	Hepatitis B virus; Chinese patent medicine; Antiviral activity; Antiviral mechanism; Selective apoptosis
Core Tip	Liuweiwuling Tablet (LWWL) exerts a potent inhibitory effect on both wild-type and drug-resistant hepatitis B virus (HBV) models. This effect appears to hinge on selective apoptosis regulation-an unprecedented discovery in the realm of anti-HBV drug mechanisms. These revelatory findings not only deepen our understanding of LWWL's anti-HBV properties but also offer an innovative mechanism to inspire the development of new anti-HBV drugs.
Publish Date	2024-04-03 07:21
Citation	Ge FL, Yang Y, Si LL, Li YH, Cao MZ, Wang J, Bai ZF, Ren ZG, Xiao XH, Liu Y. Inhibition of hepatitis B virus via selective apoptosis modulation by Chinese patent medicine Liuweiwuling Tablet. World J Gastroenterol 2024; 30(13): 1911-1925
URL	https://www.wjgnet.com/1007-9327/full/v30/i13/1911.htm
DOI	https://dx.doi.org/10.3748/wjg.v30.i13.1911

Full Article (PDF)	WJG-30-1911-with-cover.pdf
The ARRIVE Guidelines	88801-The ARRIVE guidelines.pdf
Manuscript File	88801_Auto_Edited-YJP-2024-03-08.docx
Answering Reviewers	88801-Answering reviewers.pdf
Audio Core Tip	88801-Audio core tip.mp3
Biostatistics Review Certificate	88801-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	88801-Conflict-of-interest statement.pdf
Copyright License Agreement	88801-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	88801-Grant application form(s).pdf
Institutional Animal Care and Use Committee Approval Form or Document	88801-Institutional animal care and use committee statement.pdf
Non-Native Speakers of English Editing Certificate	88801-Language certificate.pdf
Supplementary Material	88801-Supplementary material.pdf
Peer-review Report	88801-Peer-review(s).pdf
Scientific Misconduct Check	88801-Bing-Qu XL-2.jpg
Scientific Editor Work List	88801-Scientific editor work list.pdf
CrossCheck Report	88801-CrossCheck report.pdf