Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	88885
Country	China

Received	2023-10-13 17:19
Peer-Review Started	2023-10-13 17:20
To Make the First Decision
Return for Revision	2024-01-06 15:49
Revised	2024-01-19 17:14
Second Decision	2024-02-28 02:48
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-02-28 07:08
Articles in Press	2024-02-28 07:08
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-03-27 07:15
Publish the Manuscript Online	2024-04-11 02:23

ISSN	1948-5204 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Should we perform sigmoidoscopy for colorectal cancer screening in people under 45 years?
Manuscript Source	Unsolicited Manuscript
All Author List	Waiian Leong, Jia-Qi Guo, Chun Ning, Fei-Fei Luo, Rui Jiao and Dong-Ye Yang
ORCID	Author(s) ORCID Number Waiian Leong http://orcid.org/0000-0002-2530-8509 Dong-Ye Yang http://orcid.org/0000-0003-3558-8871
Funding Agency and Grant Number	Funding Agency Grant Number Shenzhen Science and Technology Innovation Commission Key Program of Fundamental Research, China JCYJ20210324120200001 Shenzhen Science and Technology Program of Shenzhen Clinical Research Center for Digestive Diseases, China 20220822182953001
Corresponding Author	Dong-Ye Yang, MD, PhD, Professor, Division of Gastroenterology & Hepatology, The University of Hong Kong-Shenzhen Hospital, No. 1 Haiyuan Street, Shenzhen 518053, Guangdong Province, China. yangdy@hku-szh.org
Key Words	Adenomatous polyps; High-grade neoplasia; Colonoscopy; Flexible sigmoidoscopy
Core Tip	This was a retrospective observational study to investigate the prevalence of adenomatous polyps (APs) and high-grade neoplasia and establish the significant difference between the left and right colon in patients aged ≤ 45 years. The prevalence of APs and high-grade neoplasia in the left colon was significantly higher than that in the right colon. This suggests that flexible sigmoidoscopy would be an optimal approach for the initial screening in people aged ≤ 45 years and would be a more cost-effective and safe strategy. Colonoscopy for post-polypectomy surveillance could be conducted at an appropriate interval of approximately 3 years.
Publish Date	2024-04-11 02:23
Citation	Leong W, Guo JQ, Ning C, Luo FF, Jiao R, Yang DY. Should we perform sigmoidoscopy for colorectal cancer screening in people under 45 years? World J Gastrointest Oncol 2024; 16(4): 1248-1255
URL	https://www.wjgnet.com/1948-5204/full/v16/i4/1248.htm
DOI	https://dx.doi.org/10.4251/wjgo.v16.i4.1248

Full Article (PDF)	WJGO-16-1248-with-cover.pdf
Manuscript File	88885_Auto_Edited-YJP.docx
Answering Reviewers	88885-Answering reviewers.pdf
Audio Core Tip	88885-Audio core tip.mp3
Biostatistics Review Certificate	88885-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	88885-Conflict-of-interest statement.pdf
Copyright License Agreement	88885-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	88885-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s)	88885-Informed consent statement.pdf
Institutional Review Board Approval Form or Document	88885-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	88885-Language certificate.pdf
Supplementary Material	88885-Supplementary material.pdf
Peer-review Report	88885-Peer-review(s).pdf
Scientific Misconduct Check	88885-Bing-Lin C-2.png
Scientific Editor Work List	88885-Scientific editor work list.pdf
CrossCheck Report	88885-CrossCheck.png
CrossCheck Report	88885-CrossCheck report.pdf