BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
2/2/2024 9:42:16 AM | Browse: 146 | Download: 906
 |
Received |
|
2023-10-14 12:31 |
|
Peer-Review Started |
|
2023-10-14 12:33 |
|
First Decision by Editorial Office Director |
|
2023-12-22 05:08 |
|
Return for Revision |
|
2023-12-22 05:08 |
|
Revised |
|
2023-12-31 11:54 |
 |
Publication Fee Transferred |
|
|
|
Second Decision by Editor |
|
2024-01-19 02:39 |
|
Second Decision by Editor-in-Chief |
|
|
|
Final Decision by Editorial Office Director |
|
2024-01-19 05:18 |
|
Articles in Press |
|
2024-01-19 05:18 |
|
Edit the Manuscript by Language Editor |
|
|
|
Typeset the Manuscript |
|
2024-01-29 01:56 |
|
Publish the Manuscript Online |
|
2024-02-02 09:42 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Minireviews |
| Article Title |
Multifaceted role of microRNAs in gastric cancer stem cells: Mechanisms and potential biomarkers
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Qian-Hui Sun, Zi-Yu Kuang, Guang-Hui Zhu, Bao-Yi Ni and Jie Li |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
82074402 |
| the Science and Technology Innovation Project of China Academy of Chinese Medical Sciences |
CI2021A01802 |
|
| Corresponding Author |
Jie Li, MD, PhD, Chief Doctor, Doctor, Doctor, Department of Oncology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, No. 5 North Line Pavilion, Xicheng District, Beijing 100053, China. qfm2020jieli@yeah.net |
| Key Words |
Gastric cancer, Cancer stem cells; MicroRNAs; Epigenetics; Therapeutic target |
| Core Tip |
Gastric cancer stem cells (GCSCs), as progenitor cells of gastric cancer (GC), are closely related to invasion, metastasis, drug resistance, and other biological processes. MicroRNAs (miRNAs) are involved in controlling the growth and differentiation mechanism of GCSC by regulating cell cycle, angiogenesis, cell invasion and migration, GCSC phenotype, and other signaling pathways. In addition, miRNAs directly or indirectly regulate the expression of tumor-promoting genes or tumor suppressor genes through different signaling pathways and it is suggested that miRNAs could be related to the initial formation of GC. In vivo, studies have shown that the biological function of GCSCs could be modulated by delivering therapeutic miRNA mimics into vivo or transgene and knockout with miRNA antagonists. It's vital to focus on whether interfering with certain miRNA levels by the methods described above leads to reversal or prevention of GC metastasis. |
| Publish Date |
2024-02-02 09:42 |
| Citation |
Sun QH, Kuang ZY, Zhu GH, Ni BY, Li J. Multifaceted role of microRNAs in gastric cancer stem cells: Mechanisms and potential biomarkers. World J Gastrointest Oncol 2024; 16(2): 300-313 |
| URL |
https://www.wjgnet.com/1948-5204/full/v16/i2/300.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v16.i2.300 |
© 2004-2026 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
