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Articles Published Processes
5/9/2024 1:59:13 PM | Browse: 497 | Download: 1368
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Received |
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2023-10-21 01:49 |
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Peer-Review Started |
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2023-10-21 01:51 |
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First Decision by Editorial Office Director |
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2024-01-25 07:13 |
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Return for Revision |
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2024-01-25 07:23 |
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Revised |
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2024-01-31 09:16 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2024-03-08 02:47 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2024-03-08 06:40 |
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Articles in Press |
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2024-03-08 06:40 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2024-04-23 07:48 |
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Publish the Manuscript Online |
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2024-05-09 13:59 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Basic Study |
| Article Title |
Predictive model using four ferroptosis-related genes accurately predicts gastric cancer prognosis
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Li Wang and Wei-Hua Gong |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Wei-Hua Gong, PhD, Researcher, Department of Surgery, The Second Affiliated Hospital Zhejiang University School of Medicine, Jiefang Road No. 88, Hangzhou 310052, Zhejiang Province, China. weihuagongzju@126.com |
| Key Words |
Ferroptosis; Gastric cancer; Helicobacter pylori infection; Immune checkpoint protein; Prognostic model; Ferroptosis-related gene prognostic index |
| Core Tip |
This study aimed to develop a prognostic model based on coregulated differentially expressed genes among ferroptosis-related genes (FRGs) in gastric cancer (GC). Gene expression profiles from GC patients and those with Helicobacter pylori-associated GC were analyzed, along with FRGs obtained from the FerrDb database. The resulting ferroptosis-related gene prognostic index (FRGPI), based on four hub genes (NOX4, MTCH1, GABARAPL2, and SLC2A3), accurately predicted GC patient survival. High-risk individuals had significantly worse overall survival, and the FRGPI was associated with disease progression and increased expression of immune checkpoint proteins. These findings provide insights into GC prognosis and immunotherapy efficacy. |
| Publish Date |
2024-05-09 13:59 |
| Citation |
Wang L, Gong WH. Predictive model using four ferroptosis-related genes accurately predicts gastric cancer prognosis. World J Gastrointest Oncol 2024; 16(5): 2018-2037
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| URL |
https://www.wjgnet.com/1948-5204/full/v16/i5/2018.htm |
| DOI |
10.4251/wjgo.v16.i5.2018 |
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