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Articles Published Processes
2/26/2024 4:10:19 AM | Browse: 50 | Download: 101
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Received |
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2023-10-23 11:14 |
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Peer-Review Started |
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2023-10-23 11:15 |
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To Make the First Decision |
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Return for Revision |
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2023-12-05 23:38 |
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Revised |
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2023-12-18 14:25 |
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Second Decision |
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2024-01-02 03:24 |
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Accepted by Journal Editor-in-Chief |
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2024-01-06 03:05 |
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Accepted by Company Editor-in-Chief |
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2024-01-29 06:33 |
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Articles in Press |
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2024-01-29 06:33 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2024-02-18 22:54 |
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Publish the Manuscript Online |
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2024-02-26 04:10 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cell Biology |
| Manuscript Type |
Minireviews |
| Article Title |
Human pluripotent stem cell-derived kidney organoids: Current progress and challenges
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Hong-Yan Long, Zu-Ping Qian, Qin Lan, Yong-Jie Xu, Jing-Jing Da, Fu-Xun Yu and Yan Zha |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
82360148 |
| Guizhou Science & Technology Department |
QKHPTRC2018-5636-2, QKHPTRC2020-2201 |
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| Corresponding Author |
Yan Zha, PhD, Chief Physician, Professor, Graduate School, Zunyi Medical University, Xinpu New District, Zunyi 563000, Guizhou Province, China. zhayan72@126.com |
| Key Words |
Kidney; Organoids; Human pluripotent stem cell; Development; Vascular system; Disease modeling |
| Core Tip |
Pluripotent stem cells (PSCs) are a class of cells with self-renewal and multidirectional differentiation potential, and organoids are a group of tissue analogues induced to form three-dimensional (3D) structures that are structurally and functionally very similar to human organs under specific differentiation conditions. We review research progress on how renal organoid induction protocols can well mimic the human foetal model of renal development and disease. The discovery of human PSCs, and the recent 3D organoid generation methods have opened avenues for in vitro mimicry of human kidney development, disease research, and testing of new drugs directly on human tissue. |
| Publish Date |
2024-02-26 04:10 |
| Citation |
Long HY, Qian ZP, Lan Q, Xu YJ, Da JJ, Yu FX, Zha Y. Human pluripotent stem cell-derived kidney organoids: Current progress and challenges. World J Stem Cells 2024; 16(2): 114-125 |
| URL |
https://www.wjgnet.com/1948-0210/full/v16/i2/114.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v16.i2.114 |
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