Publication Name	World Journal of Methodology
Manuscript ID	89196
Country	Italy

Received	2023-10-23 13:18
Peer-Review Started	2023-10-23 13:19
To Make the First Decision
Return for Revision	2023-12-06 17:41
Revised	2023-12-18 01:54
Second Decision	2024-01-12 00:58
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2024-01-27 05:02
Articles in Press	2024-01-27 05:02
Publication Fee Transferred
Edit the Manuscript by Language Editor	2024-01-30 21:13
Typeset the Manuscript	2024-02-26 10:00
Publish the Manuscript Online	2024-03-07 09:32

ISSN	2222-0682 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Medicine, General & Internal
Manuscript Type	Review
Article Title	Update on the gut microbiome in health and diseases
Manuscript Source	Invited Manuscript
All Author List	Maurizio Salvadori and Giuseppina Rosso
ORCID	Author(s) ORCID Number Maurizio Salvadori http://orcid.org/0000-0003-1503-2681 Giuseppina Rosso http://orcid.org/0009-0005-1014-9866
Funding Agency and Grant Number
Corresponding Author	Maurizio Salvadori, MD, Professor, Department of Renal Transplantation, Careggi University Hospital, Viale Pieraccini 18, Florence 50139, Tuscany, Italy. maurizio.salvadori1@gmail.com
Key Words	Gut microbiome; Dysbiosis; Pathobionts; Gut-brain axis; Heart-brain axis; Metabolic diseases; Omics techniques
Core Tip	Gut microbiome has a relevant importance in healthy and diseased subjects. The production of several metabolites from the gut microbiome influences immune system, brain, lung, heart and metabolism. In the case of normal indigenous microbiota, metabolites produced have a benign action and contribute to the health. In contrast, the presence of pathobionts with their products may affect the different organs and produce diseases. The study of the gut microbiome is a difficult one and different omics technologies should be applied. The large quantity of studies witness and highlights the relevance of the gut microbiome in health and disease.
Publish Date	2024-03-07 09:32
Citation	Salvadori M, Rosso G. Update on the gut microbiome in health and diseases. World J Methodol 2024; 14(1): 89196
URL	https://www.wjgnet.com/2222-0682/full/v14/i1/89196.htm
DOI	https://dx.doi.org/10.5662/wjm.v14.i1.89196

Full Article (PDF)	WJM-14-89196-with-cover.pdf
Manuscript File	89196-Review-FilipodiaCL.docx
Answering Reviewers	89196-Answering reviewers.pdf
Audio Core Tip	89196-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	89196-Conflict-of-interest statement.pdf
Copyright License Agreement	89196-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	89196-Language certificate.pdf
Peer-review Report	89196-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	89196-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	89196-CrossCheck.png
Scientific Misconduct Check	89196-Bing-Liu JH-2.png
Scientific Editor Work List	89196-Scientific editor work list.pdf