| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
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| Permissions |
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Endocrinology & Metabolism |
| Manuscript Type |
Clinical and Translational Research |
| Article Title |
Investigating the causal associations between five anthropometric indicators and nonalcoholic fatty liver disease: Mendelian randomization study
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Xian-Pei Xiao, Yu Zhang, Yong-Jun Dai, Meng Yang, Jian Xie, Guo Chen and Zheng-Jun Yang |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Science and Technology Research Project of Sichuan Administration of Traditional Chinese Medicine |
2023MS419 |
|
| Corresponding Author |
Zheng-Jun Yang, MD, Doctor, Department of Oncology, Luojiang District People's Hospital of Deyang City, No. 286 Wanan South Road, Deyang 618000, Sichuan Province, China. 850006775@qq.com |
| Key Words |
Anthropometric indicator; Waist circumference; Nonalcoholic fatty liver disease; Mendelian randomization; Genetic variant |
| Core Tip |
Previous studies have demonstrated the potential significance of anthropometric indicators in the development of nonalcoholic fatty liver disease (NAFLD). Nevertheless, inconsistencies exist in the results of these studies, and the causal association remains unclear. Abdominal obesity, measured by waist circumference (WC), is a risk factor for NAFLD, as demonstrated by previous studies. Nevertheless, many of these studies were cross-sectional or considered only a single measurement, neglecting a comprehensive evaluation of changes in WC over time and the effect of long-term development and lifestyle changes. Consequently, establishing a causal relationship between anthropometric indicators and NAFLD requires further robust evidence. |
| Publish Date |
2024-03-01 02:45 |
| Citation |
Xiao XP, Zhang Y, Dai YJ, Yang M, Xie J, Chen G, Yang ZJ. Investigating the causal associations between five anthropometric indicators and nonalcoholic fatty liver disease: Mendelian randomization study. World J Clin Cases 2024; 12(7): 1215-1226 |
| URL |
https://www.wjgnet.com/2307-8960/full/v12/i7/1215.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v12.i7.1215 |
