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3/12/2024 10:04:17 AM | Browse: 48 | Download: 48
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 89389
Country China
Received
2023-10-30 10:16
Peer-Review Started
2023-10-30 10:18
To Make the First Decision
Return for Revision
2023-12-06 07:21
Revised
2023-12-16 04:59
Second Decision
2024-01-17 02:54
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2024-01-17 07:57
Articles in Press
2024-01-17 07:57
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2024-02-18 07:32
Publish the Manuscript Online
2024-03-12 10:04
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Basic Study
Article Title Long non-coding RNA GATA6-AS1 is mediated by N6-methyladenosine methylation and inhibits the proliferation and metastasis of gastric cancer
Manuscript Source Unsolicited Manuscript
All Author List Jun-Jie Shen, Min-Chang Li, Shao-Qi Tian and Wen-Ming Chen
ORCID
Author(s) ORCID Number
Jun-Jie Shen http://orcid.org/0000-0002-0006-7438
Min-Chang Li http://orcid.org/0009-0000-5606-2663
Shao-Qi Tian http://orcid.org/0009-0004-2208-0387
Wen-Ming Chen http://orcid.org/0000-0002-9366-2745
Funding Agency and Grant Number
Funding Agency Grant Number
Natural Science Foundation of Shandong Province No. ZR2020MH207 and No. ZR2020MH251
Corresponding Author Wen-Ming Chen, MD, Associate Chief Physician, Department of Oncology, Jining First People’s Hospital, Jining 272011, Shandong Province, China. yusuker9950529@163.com
Key Words Long non-coding RNA; GATA6-AS1; N6-methyladenine modification; Fat mass and obesity-associated protein; Gastric cancer
Core Tip Long non-coding RNA GATA6-AS1 is down-regulated in gastric malignant tumor, and capable to inhibit the proliferation, migration and invasion of tumor cells, acting as a tumor suppressor gene in gastric cancer cells. Fat mass and obesity-associated protein (FTO) is highly expressed in gastric cancer, and the down-regulation of GATA6-AS1 in gastric cancer is regulated by the N6-methyladenine demethylase FTO. Therefore, during the occurrence and development of gastric cancer, overexpressed FTO may inhibit the expression of GATA6-AS1, thus promoting the proliferation and metastasis of gastric cancer.
Publish Date 2024-03-12 10:04
Citation Shen JJ, Li MC, Tian SQ, Chen WM. Long non-coding RNA GATA6-AS1 is mediated by N6-methyladenosine methylation and inhibits the proliferation and metastasis of gastric cancer. World J Gastrointest Oncol 2024; 16(3): 1019-1028
URL https://www.wjgnet.com/1948-5204/full/v16/i3/1019.htm
DOI https://dx.doi.org/10.4251/wjgo.v16.i3.1019
Full Article (PDF) WJGO-16-1019-with-cover.pdf
Full Article (Word) WJGO-16-1019.docx
Manuscript File 89389_Auto_Edited-JLW.docx
Answering Reviewers 89389-Answering reviewers.pdf
Audio Core Tip 89389-Audio core tip.mp3
Biostatistics Review Certificate 89389-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 89389-Conflict-of-interest statement.pdf
Copyright License Agreement 89389-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 89389-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate 89389-Language certificate.pdf
Peer-review Report 89389-Peer-review(s).pdf
Scientific Misconduct Check 89389-Bing-Qu XL-2.jpg
Scientific Editor Work List 89389-Scientific editor work list.pdf