Publication Name	World Journal of Gastroenterology
Manuscript ID	8940
Country	France

Received	2014-01-13 11:48
Peer-Review Started	2014-01-23 14:07
To Make the First Decision	2014-02-14 14:02
Return for Revision	2014-02-20 09:41
Revised	2014-03-18 08:01
Second Decision	2014-06-17 09:16
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-06-17 09:48
Articles in Press	2014-06-17 10:10
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-10-10 11:52
Publish the Manuscript Online	2014-10-20 18:35

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Liver resection and metabolic disorders: An undescribed mechanism leading to postoperative mortality
Manuscript Source	Unsolicited Manuscript
All Author List	Alban Zarzavadjian Le Bian, Renato Costi, Mohamed Said Sbai-Idrissi and Claude Smadja
Funding Agency and Grant Number
Corresponding Author	Alban Zarzavadjian Le Bian, MD, MPh, Laboratoire d’Ethique Médicale et de Médecine Légale, Université Paris Descartes-V, 45 rue des Saints Pères, 75006 Paris, France. spleen2008@live.fr
Key Words	Metabolic syndrome; Major hepatectomy; Liver resection; Postoperative mortality; Hepatorenal syndrome
Core Tip	Patients who passed away during perioperative course of major liver resection and presenting with the association of ≥ 2 metabolic disorders without any other known cause of liver disorders were reviewed. The same four-consecutive-steps sequence of events occurred, including jaundice/ascites, renal failure, hemodynamic collapse with inotrope use and death. The analysis suggested a rapidly deteriorating congestive liver resulting in an increased portal hypertension leading to hepatorenal syndrome and lately to multiorgan failure as the mechanism leading to exitus. As fibrosis was marginal in liver specimens, cause of portal hypertension in patients with multiple metabolic disorders should be investigated with further studies.
Publish Date	2014-10-20 18:35
Citation	Zarzavadjian Le Bian A, Costi R, Sbai-Idrissi MS, Smadja C. Liver resection and metabolic disorders: An undescribed mechanism leading to postoperative mortality. World J Gastroenterol 2014; 20(39): 14455-14462
URL	http://www.wjgnet.com/1007-9327/full/v20/i39/14455.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i39.14455

Full Article (PDF)	WJG-20-14455.pdf
Full Article (Word)	WJG-20-14455.doc
Manuscript File	8940-Review.doc
Answering Reviewers	8940-Answering reviewers.pdf
Copyright License Agreement	8940-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	8940-Language certificate.pdf
Peer-review Report	8940-Peer reviews.pdf
Scientific Misconduct Check	8940-CrossCheck.jpg
Scientific Editor Work List	8940-Scientific editor work list.pdf