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Articles Published Processes
3/12/2024 10:04:17 AM | Browse: 263 | Download: 1257
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Received |
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2023-11-03 13:42 |
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Peer-Review Started |
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2023-11-03 13:44 |
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First Decision by Editorial Office Director |
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2023-12-01 18:14 |
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Return for Revision |
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2023-12-01 18:14 |
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Revised |
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2023-12-12 17:12 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2024-01-10 02:42 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2024-01-10 05:12 |
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Articles in Press |
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2024-01-10 05:12 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2024-01-29 07:39 |
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Publish the Manuscript Online |
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2024-03-12 10:04 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Comparison of mismatch repair and immune checkpoint protein profile with histopathological parameters in pancreatic, periampullary/ampullary, and choledochal adenocarcinomas
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Arzu Hazal Aydın and Nesrin Turhan |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Arzu Hazal Aydın, MD, Doctor, Doctor, Department of Pathology, Aksaray University Aksaray Training and Research Hospital, Sifahane District, No. 3152 Street, Aksaray 68200, Türkiye. arzu.hazal.aydin@gmail.com |
| Key Words |
H long terminal repeat-associating 2; Programmed death-ligand 1; Adenocarcinoma; Pancreas; Ampulla of Vater; Distal common bile duct |
| Core Tip |
Pancreatic, periampullary/ampullary, and choledochal adenocarcinomas are aggressive malignancies with recurrences and metastases occurring in a short period of time. Complete resection is possible in only a small proportion of patients; thus, targeted therapies are needed. H long terminal repeat-associating 2 (HHLA2), which is analogous to programmed death-ligand 1 (PD-L1), is expressed in many malignancies. Evaluation of HHLA2 expression in microsatellite stable and PD-L1-negative tumors may be useful for predicting the response of individuals to immunotherapy, and may serve as a novel therapeutic target in patients with advanced disease who do not respond to classical chemotherapy and have unresectable cancer. |
| Publish Date |
2024-03-12 10:04 |
| Citation |
Aydın AH, Turhan N. Comparison of mismatch repair and immune checkpoint protein profile with histopathological parameters in pancreatic, periampullary/ampullary, and choledochal adenocarcinomas. World J Gastrointest Oncol 2024; 16(3): 875-882 |
| URL |
https://www.wjgnet.com/1948-5204/full/v16/i3/875.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v16.i3.875 |
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