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Articles Published Processes
2/2/2024 9:42:16 AM | Browse: 316 | Download: 1416
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Received |
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2023-11-07 13:48 |
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Peer-Review Started |
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2023-11-07 13:49 |
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First Decision by Editorial Office Director |
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2023-12-04 02:46 |
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Return for Revision |
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2023-12-04 13:41 |
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Revised |
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2023-12-09 08:01 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2024-01-04 02:49 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2024-01-04 06:26 |
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Articles in Press |
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2024-01-04 06:26 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2024-01-27 05:04 |
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Publish the Manuscript Online |
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2024-02-02 09:42 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Pathology |
| Manuscript Type |
Case Report |
| Article Title |
Early adenocarcinoma mixed with a neuroendocrine carcinoma component arising in the gastroesophageal junction: A case report
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yu-Qing Cheng, Geng-Fang Wang, Xiao-Li Zhou, Min Lin, Xin-Wen Zhang and Qin Huang |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Changzhou High-level Medical Talents Training Project of the Health Commission of the Changzhou City |
2022CZBJ079 |
| Changzhou Sci&Tech Program |
CE20235064 |
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| Corresponding Author |
Qin Huang, MD, PhD, Chief Doctor, Department of Pathology, the Affiliated Changzhou No. 2 People’s Hospital of Nanjing Medical University, No. 68 Gehu Road, Wujin District, Changzhou 213164, Jiangsu Province, China. qinhuang0122@gmail.com |
| Key Words |
Adenocarcinoma; Neuroendocrine carcinoma; Gastroesophageal junction; Next generation sequencing; Case report |
| Core Tip |
We report a 29-year-old man with a 1.5-cm intramucosal adenocarcinoma with a neuroendocrine carcinoma component, which arose in the columnar-lined esophagus within 1.6 cm above the gastroesophageal junction (GEJ), without Barrett’s esophagus. Next-generation sequencing revealed a novel germline mutation of the ERCC3 gene in the DNA repair pathway of gastric cancer and a germline mutation of the RNF43 gene as a tumor suppressor in gastric cancer. Our findings suggest this early-onset GEJ carcinoma originated from gastric cardiac mucosa with genetic abnormalities involved in the DNA repair pathway. |
| Publish Date |
2024-02-02 09:42 |
| Citation |
Cheng YQ, Wang GF, Zhou XL, Lin M, Zhang XW, Huang Q. Early adenocarcinoma mixed with a neuroendocrine carcinoma component arising in the gastroesophageal junction: A case report. World J Gastrointest Oncol 2024; 16(2): 563-570 |
| URL |
https://www.wjgnet.com/1948-5204/full/v16/i2/563.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v16.i2.563 |
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