Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	89678
Country	China

Received	2023-11-09 02:51
Peer-Review Started	2023-11-09 02:54
To Make the First Decision
Return for Revision	2023-12-18 08:44
Revised	2023-12-28 14:49
Second Decision	2024-01-16 02:44
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2024-01-16 05:45
Articles in Press	2024-01-16 05:45
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-03-01 07:29
Publish the Manuscript Online	2024-03-12 10:04

ISSN	1948-5204 (online)
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Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Unraveling the enigma: A comprehensive review of solid pseudopapillary tumor of the pancreas
Manuscript Source	Invited Manuscript
All Author List	Ye-Cheng Xu, De-Liang Fu and Feng Yang
ORCID	Author(s) ORCID Number Ye-Cheng Xu http://orcid.org/0000-0001-8678-4843 De-Liang Fu http://orcid.org/0000-0003-4060-8101 Feng Yang http://orcid.org/0000-0001-8790-6072
Funding Agency and Grant Number
Corresponding Author	Feng Yang, MD, PhD, Doctor, Surgeon, Department of Pancreatic Surgery, Pancreatic Disease Institute, Huashan Hospital, Fudan University, No. 12 Central Urumqi Road, Shanghai 200040, China. yffudan98@126.com
Key Words	Pancreas; Solid pseudopapillary tumor; β-catenin; Endoscopic ultrasound; Surgery; Recurrence; Liver metastasis; Prognostic prediction
Core Tip	Solid pseudopapillary tumor of the pancreas (SPTP) is a rare neoplasm predominantly affecting young females. Pathologically, CTNNB1 mutations, β-catenin nuclear accumulation, and Wnt signaling pathway activation are key molecular features. Accurate preoperative diagnosis relies on imaging and endoscopic biopsies. Surgical resection is the main treatment, and prognostic models like Fudan Prognostic Index aid in prognosis assessment. Challenges in understanding its etiology, establishing treatments for unresectable/metastatic disease, and developing a standardized grading system persist. This comprehensive review aims to consolidate current knowledge on epidemiology, clinical presentation, pathology, molecular features, and treatment options for SPTP.
Publish Date	2024-03-12 10:04
Citation	Xu YC, Fu DL, Yang F. Unraveling the enigma: A comprehensive review of solid pseudopapillary tumor of the pancreas. World J Gastrointest Oncol 2024; 16(3): 614-629
URL	https://www.wjgnet.com/1948-5204/full/v16/i3/614.htm
DOI	https://dx.doi.org/10.4251/wjgo.v16.i3.614

Full Article (PDF)	WJGO-16-614-with-cover.pdf
Full Article (Word)	WJGO-16-614.docx
Manuscript File	89678_Auto_Edited-YJP.docx
Answering Reviewers	89678-Answering reviewers.pdf
Audio Core Tip	89678-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	89678-Conflict-of-interest statement.pdf
Copyright License Agreement	89678-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	89678-Language certificate.pdf
Peer-review Report	89678-Peer-review(s).pdf
Scientific Misconduct Check	89678-Bing-Yan JP-2.png
Scientific Editor Work List	89678-Scientific editor work list.pdf