Publication Name	World Journal of Gastroenterology
Manuscript ID	89684
Country	China

Received	2023-11-09 05:39
Peer-Review Started	2023-11-09 05:41
To Make the First Decision
Return for Revision	2023-12-15 04:29
Revised	2024-01-05 02:20
Second Decision	2024-02-20 02:52
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-02-20 06:03
Articles in Press	2024-02-20 06:03
Publication Fee Transferred
Edit the Manuscript by Language Editor	2024-02-07 00:38
Typeset the Manuscript	2024-03-04 05:53
Publish the Manuscript Online	2024-03-21 11:37

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Morphological and biochemical characteristics associated with autophagy in gastrointestinal diseases
Manuscript Source	Unsolicited Manuscript
All Author List	Yi-Fan Chang, Jia-Jing Li, Tao Liu, Chong-Qing Wei, Li-Wei Ma, Vladimir N Nikolenko and Wei-Long Chang
ORCID	Author(s) ORCID Number Yi-Fan Chang http://orcid.org/0009-0001-2080-1644 Vladimir N Nikolenko http://orcid.org/0000-0001-9532-9957 Wei-Long Chang http://orcid.org/0009-0007-0822-0592
Funding Agency and Grant Number	Funding Agency Grant Number Natural Science Foundation of China 81900533 Technology Project of Henan Science and Technology Department 232102520032
Corresponding Author	Wei-Long Chang, PhD, Doctor, Doctor, Department of Gastrointestinal Surgery, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe East Road, Erqi District, Zhengzhou 450000, Henan Province, China. changwl365@foxmail.com
Key Words	Autophagy; Morphological study; Biochemical characteristics; Subcellular structure; Transmission electron microscopy; Gastrointestinal diseases
Core Tip	Autophagy, from a morphological standpoint, shares similarities with other biological processes such as phagocytosis and apoptosis. As an intracellular catabolic mechanism, autophagy, along with the ubiquitin-proteasome system, contributes to maintaining cellular homeostasis. Moreover, autophagy also assumes a role in programmed cell death when apoptosis is absent. Numerous studies have established the close association between autophagy and the physiological functions of different gastrointestinal (GI) cells. Morphological investigations have furnished substantial evidence highlighting autophagy's pro-survival role in benign conditions like intestinal ischemia-reperfusion injury, inflammatory bowel disease, and GI motility disorders. Further research into the involvement of autophagy in GI tumors is necessary to unravel these unresolved mysteries in the future.
Publish Date	2024-03-21 11:37
Citation	Chang YF, Li JJ, Liu T, Wei CQ, Ma LW, Nikolenko VN, Chang WL. Morphological and biochemical characteristics associated with autophagy in gastrointestinal diseases. World J Gastroenterol 2024; 30(11): 1524-1532
URL	https://www.wjgnet.com/1007-9327/full/v30/i11/1524.htm
DOI	https://dx.doi.org/10.3748/wjg.v30.i11.1524

Full Article (PDF)	WJG-30-1524-with-cover.pdf
Manuscript File	89684_Auto_Edited-YJP-WangTQ-YJP.docx
Answering Reviewers	89684-Answering reviewers.pdf
Audio Core Tip	89684-Audio core tip.aac
Conflict-of-Interest Disclosure Form	89684-Conflict-of-interest statement.pdf
Copyright License Agreement	89684-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	89684-Grant application form(s).pdf
Peer-review Report	89684-Peer-review(s).pdf
Scientific Misconduct Check	89684-Bing-Yan JP-2.png
Scientific Editor Work List	89684-Scientific editor work list.pdf
CrossCheck Report	89684-CrossCheck report.pdf