| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Clinical manifestations, diagnosis and long-term prognosis of adult autoimmune enteropathy: Experience from Peking Union Medical College Hospital
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Mu-Han Li, Ge-Chong Ruan, Wei-Xun Zhou, Xiao-Qing Li, Sheng-Yu Zhang, Yang Chen, Xiao-Yin Bai, Hong Yang, Yu-Jie Zhang, Peng-Yu Zhao, Ji Li and Jing-Nan Li |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National High Level Hospital Clinical Research Funding |
2022-PUMCH-B-022 |
| National High Level Hospital Clinical Research Funding |
2022-PUMCH-D-002 |
| CAMS Innovation Fund for Medical Sciences |
2021-1-I2M- 003 |
| Undergraduate Innovation Program |
2023-zglc-06034 |
| National key clinical specialty construction project |
ZK108000 |
|
| Corresponding Author |
Ji Li, MD, Professor, Department of Gastroenterology, Chinese Academy of Medical Sciences & Peking Union Medical College Hospital, No. 1 Shuaifuyuan, Wangfujing, Beijing 100730, China. liji0235@pumch.cn |
| Key Words |
Autoimmune enteropathy; Clinical manifestations; Diagnostic criteria; Pathological features; Long-term prognosis |
| Core Tip |
Autoimmune enteropathy (AIE) is a rare disease with heterogeneous manifestations and continually evolving diagnostic criteria. In adults, the presence of secretory diarrhea alongside specific histopathological findings can indicate the possibility of AIE. Histopathological features such as decreased goblet and Paneth cells might serve as potential diagnostic criteria. Despite treatment involving corticosteroids and immunosuppressants, long-term prognosis remains unsatisfactory, underscoring the pressing need for early diagnosis and innovative therapeutic approaches. |
| Publish Date |
2024-05-20 09:15 |
| Citation |
<p>Li MH, Ruan GC, Zhou WX, Li XQ, Zhang SY, Chen Y, Bai XY, Yang H, Zhang YJ, Zhao PY, Li J, Li JN. Clinical manifestations, diagnosis and long-term prognosis of adult autoimmune enteropathy: Experience from Peking Union Medical College Hospital. <i>World J Gastroenterol</i> 2024; 30(19): 2523-2537</p> |
| URL |
https://www.wjgnet.com/1007-9327/full/v30/i19/2523.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v30.i19.2523 |
