Publication Name	World Journal of Clinical Cases
Manuscript ID	90125
Country	Türkiye

Received	2023-11-23 18:57
Peer-Review Started	2023-11-23 18:58
To Make the First Decision
Return for Revision	2023-11-28 07:54
Revised	2023-12-07 18:07
Second Decision	2023-12-25 02:48
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2023-12-25 07:59
Articles in Press	2023-12-25 07:59
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-01-03 02:52
Publish the Manuscript Online	2024-01-18 09:11

ISSN	2307-8960 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Biochemistry & Molecular Biology
Manuscript Type	Editorial
Article Title	Metabologenomics and network pharmacology to understand the molecular mechanism of cancer research
Manuscript Source	Invited Manuscript
All Author List	Yusuf Tutar
ORCID	Author(s) ORCID Number Yusuf Tutar http://orcid.org/0000-0003-2613-9644
Funding Agency and Grant Number
Corresponding Author	Yusuf Tutar, BSc, MSc, PhD, Academic Editor, Chairman, Dean, Full Professor, Science Editor, Senior Scientist, Department of Basic Pharmaceutical Sciences, Faculty of Pharmacy, Division of Biochemistry, University of Health Sciences, Mekteb-i Tıbbiye-i Şahane (Hamidiye) Külliyesi Selimiye Mah Tıbbiye Cad, Istanbul 34668, Türkiye. ytutar@outlook.com
Key Words	Network pharmacology; Metabologenomics; Genome; Pathways; Cancer
Core Tip	Regulation of biochemical pathways is similar to Le Chatelier chemical dynamic equilibrium principle. It states that the equilibrium is disrupted by changing the conditions, and the position of dynamic equilibrium shifts to counteract the change to reestablish an equilibrium. Metabolites disrupt pathways either themselves or by enhancing gene expression levels. The equilibrium or “homeostasis” always reestablishes itself to survive the organism. The relationship between genes and metabolites may be discovered by understanding the link through computational networking.
Publish Date	2024-01-18 09:11
Citation	Tutar Y. Metabologenomics and network pharmacology to understand the molecular mechanism of cancer research. World J Clin Cases 2024; 12(3): 474-478
URL	https://www.wjgnet.com/2307-8960/full/v12/i3/474.htm
DOI	https://dx.doi.org/10.12998/wjcc.v12.i3.474

Full Article (PDF)	WJCC-12-474-with-cover.pdf
Full Article (Word)	WJCC-12-474.docx
Manuscript File	90125_Auto_Edited-YJP.docx
Answering Reviewers	90125-Answering reviewers.pdf
Audio Core Tip	90125-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	90125-Conflict-of-interest statement.pdf
Copyright License Agreement	90125-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	90125-Language certificate.pdf
Peer-review Report	90125-Peer-review(s).pdf
Scientific Misconduct Check	90125-Bing-Li L-2.png
Scientific Editor Work List	90125-Scientific editor work list.pdf
CrossCheck Report	90125-CrossCheck report.pdf
CrossCheck Report	90125-CrossCheck.png