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Articles Published Processes
3/19/2024 10:56:31 AM | Browse: 213 | Download: 677
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Received |
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2023-11-30 09:02 |
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Peer-Review Started |
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2023-11-30 09:02 |
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To Make the First Decision |
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Return for Revision |
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2023-12-18 06:53 |
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Revised |
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2023-12-25 03:06 |
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Second Decision |
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2024-02-04 03:02 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2024-02-04 06:22 |
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Articles in Press |
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2024-02-04 06:22 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2024-03-07 06:41 |
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Publish the Manuscript Online |
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2024-03-19 10:56 |
| ISSN |
2220-3206 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Psychiatry |
| Manuscript Type |
Observational Study |
| Article Title |
Causal relationship between feelings and cognitive decline: An univariable and multivariable Mendelian randomization study
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Juan Liu, Lin Liu, Yi-Xin Hu, Jian-Hua Li, Xiao Zou, Hao-Yun Zhang and Li Fan |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Li Fan, MD, PhD, Dean, Cardiology Department of The Second Medical Center & National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital, No. 28 Fuxing Road, Beijing 100853, China. fanl301@163.com |
| Key Words |
Mendelian randomization analysis; Feelings; Cognition; Intelligence |
| Core Tip |
Our two-sample Mendelian randomization (MR) analysis investigated the relationship between various emotions and cognitive function in the European population. We found compelling genetic evidence suggesting that sensitivity/hurt feelings may have a negative causal effect on cognition, even after adjusting for other emotional factors. In contrast, the causal link between worrier/anxious feelings and cognition remains inconclusive due to pleiotropy. Additionally, we did not find significant associations between happiness, guilty feelings, nervous feelings, miserableness, loneliness/isolation, and cognitive decline. This study sheds light on the complex interplay between emotions and cognition, highlighting the importance of sensitivity/hurt feelings in cognitive health. |
| Publish Date |
2024-03-19 10:56 |
| Citation |
Liu J, Liu L, Hu YX, Li JH, Zou X, Zhang HY, Fan L. Causal relationship between feelings and cognitive decline: An univariable and multivariable Mendelian randomization study. World J Psychiatry 2024; 14(3): 421-433 |
| URL |
https://www.wjgnet.com/2220-3206/full/v14/i3/421.htm |
| DOI |
https://dx.doi.org/10.5498/wjp.v14.i3.421 |
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