Publication Name	World Journal of Diabetes
Manuscript ID	90256
Country	India

Received	2023-11-28 11:22
Peer-Review Started	2023-11-28 11:24
To Make the First Decision
Return for Revision	2024-01-15 07:29
Revised	2024-01-15 16:51
Second Decision	2024-02-06 02:45
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-02-06 05:51
Articles in Press	2024-02-06 05:51
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-03-07 03:35
Publish the Manuscript Online	2024-03-15 09:49

ISSN	1948-9358 (online)
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Category	Endocrinology & Metabolism
Manuscript Type	Letter to the Editor
Article Title	Regulatory role of peroxynitrite in advanced glycation end products mediated diabetic cardiovascular complications
Manuscript Source	Unsolicited Manuscript
All Author List	Asis Bala
ORCID	Author(s) ORCID Number Asis Bala http://orcid.org/0000-0002-2148-2331
Funding Agency and Grant Number
Corresponding Author	Asis Bala, PhD, Associate Professor, Pharmacology and Drug Discovery Research Laboratory, Division of Life Sciences, Institute of Advanced Study in Science and Technology, Vigyan Path, Guwahati 781035, Assam, India. asisbala@iasst.gov.in
Key Words	Diabetes; Cardiovascular complication; Advanced glycation end products; Reactive oxygen species; Reactive nitrogen species; Peroxynitrite
Core Tip	The binding of Advanced Glycation End Products (AGE) to its receptor triggers the activation of signaling mediators that promote the generation of reactive oxygen species (ROS). The impact of ROS on the body can be beneficial or harmful, depending on its concentration and location. In diabetic cardiovascular complications, peroxynitrite (ONOO-) plays a crucial role in vascular changes. ROS, derived from NADPH oxidase, regulates host immune responses and cellular inflammation. The production of superoxide (O2-), hydrogen peroxide (H2O2), and other compounds occurs as oxygen undergoes a series of reductions. It is essential to consider the presence of ONOO- in AGEs in diabetic cardiovascular complications.
Publish Date	2024-03-15 09:49
Citation	Bala A. Regulatory role of peroxynitrite in advanced glycation end products mediated diabetic cardiovascular complications. World J Diabetes 2024; 15(3): 572-574
URL	https://www.wjgnet.com/1948-9358/full/v15/i3/572.htm
DOI	https://dx.doi.org/10.4239/wjd.v15.i3.572

Full Article (PDF)	WJD-15-572-with-cover.pdf
Full Article (Word)	WJD-15-572.docx
Manuscript File	90256_Auto_Edited-YJP.docx
Answering Reviewers	90256-Answering reviewers.pdf
Audio Core Tip	90256-Audio core tip.aac
Conflict-of-Interest Disclosure Form	90256-Conflict-of-interest statement.pdf
Copyright License Agreement	90256-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	90256-Language certificate.pdf
Peer-review Report	90256-Peer-review(s).pdf
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Scientific Editor Work List	90256-Scientific editor work list.pdf
CrossCheck Report	90256-CrossCheck.png
CrossCheck Report	90256-CrossCheck report.pdf