| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Prospective Study |
| Article Title |
Characterization of acute-on-chronic liver diseases: A multicenter prospective cohort study
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yuan-Yao Zhang, Sen Luo, Hai Li, Shu-Ning Sun, Xian-Bo Wang, Xin Zheng, Yan Huang, Bei-Ling Li, Yan-Hang Gao, Zhi-Ping Qian, Feng Liu, Xiao-Bo Lu, Jun-Ping Liu, Hao-Tang Ren, Yu-Bao Zheng, Hua-Dong Yan, Guo-Hong Deng, Liang Qiao, Yan Zhang, Wen-Yi Gu, Xiao-Mei Xiang, Yi Zhou, Yi-Xin Hou, Qun Zhang, Yan Xiong, Cong-Cong Zou, Jun Chen, Ze-Bing Huang, Xiu-Hua Jiang, Ting-Ting Qi, Yuan-Yuan Chen, Na Gao, Chun-Yan Liu, Wei Yuan, Xue Mei, Jing Li, Tao Li, Rong-Jiong Zheng, Xin-Yi Zhou, Jun Zhao and Zhong-Ji Meng |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| The National Science and Technology Major Project |
2018ZX10723203 and 2018ZX10302206 |
| Hubei Province’s Outstanding Medical Academic Leader Program, Advantage Discipline Group (Public Health) Project in Higher Education of Hubei Province |
2023PHXKQ1 |
| The Foundation of Health Commission of Hubei Province |
WJ2021F037 and WJ2021M051 |
| Project of Hubei University of Medicine |
FDFR201902 and YC2023047 |
| The Hubei Provincial Technology Innovation Project |
2023BCB129 |
|
| Corresponding Author |
Zhong-Ji Meng, MD, Chief Doctor, Full Professor, Research Scientist, Department of Infectious Disease, Taihe Hospital, Hubei University of Medicine, No. 32 South Renmin Road, Shiyan 442000, Hubei Province, China. zhongji.meng@163.com |
| Key Words |
Acute-on-chronic liver disease; Acute-on-chronic liver failure; Liver cirrhosis; Clinical features; Prognosis |
| Core Tip |
This study systematically investigated the composition, clinical characteristics, and prognosis of each subtype of acute-on-chronic liver disease (AoCLD) for the first time. In China, liver cirrhosis acute decompensation (LC-AD) is the most common clinical type of AoCLD, with a high short-term mortality rate. Attention should be given to the early diagnosis and intervention of patients with LC-AD to avoid acute decompensation-acute-on-chronic liver failure (ACLF) transition. Type C ACLF patients have the highest mortality rate, requiring early liver transplantation to improve the overall survival rate of AoCLD. |
| Publish Date |
2024-05-22 11:33 |
| Citation |
<p>Zhang YY, Luo S, Li H, Sun SN, Wang XB, Zheng X, Huang Y, Li BL, Gao YH, Qian ZP, Liu F, Lu XB, Liu JP, Ren HT, Zheng YB, Yan HD, Deng GH, Qiao L, Zhang Y, Gu WY, Xiang XM, Zhou Y, Hou YX, Zhang Q, Xiong Y, Zou CC, Chen J, Huang ZB, Jiang XH, Qi TT, Chen YY, Gao N, Liu CY, Yuan W, Mei X, Li J, Li T, Zheng RJ, Zhou XY, Zhao J, Meng ZJ. Characterization of acute-on-chronic liver diseases: A multicenter prospective cohort study. <i>World J Hepatol</i> 2024; 16(5): 809-821</p> |
| URL |
https://www.wjgnet.com/1948-5182/full/v16/i5/809.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v16.i5.809 |
