Publication Name	World Journal of Cardiology
Manuscript ID	90340
Country	Greece

Received	2023-11-30 10:57
Peer-Review Started	2023-11-30 10:57
To Make the First Decision
Return for Revision	2024-03-30 20:55
Revised	2024-04-18 07:45
Second Decision	2024-05-13 02:40
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-05-13 05:53
Articles in Press	2024-05-13 05:53
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-05-14 08:24
Publish the Manuscript Online	2024-05-23 12:52

ISSN	1949-8462 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Cardiac & Cardiovascular Systems
Manuscript Type	Editorial
Article Title	Congenital heart “Challenges” in Down syndrome
Manuscript Source	Invited Manuscript
All Author List	Maria Drakopoulou, Panayotis K Vlachakis, Costas Tsioufis and Dimitris Tousoulis
ORCID	Author(s) ORCID Number Maria Drakopoulou http://orcid.org/0000-0002-0022-0332 Panayotis K Vlachakis http://orcid.org/0000-0003-0736-4942 Costas Tsioufis http://orcid.org/0000-0002-7636-6725 Dimitris Tousoulis http://orcid.org/0000-0001-7492-4984
Funding Agency and Grant Number
Corresponding Author	Maria Drakopoulou, FESC, MD, MSc, PhD, Lecturer, Department of First Cardiology, Hippokration General Hospital, Athens Medical School, National and Kapodistrian University of Athens, 114 Vasilissis Sophia Avenue, Athens 11527, Greece. mdrakopoulou@hotmail.com
Key Words	Down syndrome; Congenital heart disease; Atrioventricular septal defect; Pulmonary hypertension; Right heart catheterization
Core Tip	Addressing the health challenges of individuals with Down syndrome (DS) poses intricate challenges, with congenital heart disease (CHD) being notably prevalent. The complexity of managing DS and CHD is heightened by diagnostic delays and difficulties in symptom assessment due to intellectual disabilities. Incorporating this unique population into comprehensive studies and randomized trials, with careful consideration of informed consent and a multidisciplinary research framework, is crucial.
Publish Date	2024-05-23 12:52
Citation	<p>Drakopoulou M, Vlachakis PK, Tsioufis C, Tousoulis D. Congenital heart “Challenges” in Down syndrome. <i>World J Cardiol</i> 2024; 16(5): 217-220</p>
URL	https://www.wjgnet.com/1949-8462/full/v16/i5/217.htm
DOI	https://dx.doi.org/10.4330/wjc.v16.i5.217

Full Article (PDF)	WJC-16-217-with-cover.pdf
Manuscript File	90340_Auto_Edited-YJP.docx
Answering Reviewers	90340-answering-reviewers.pdf
Audio Core Tip	90340-audio.m4a
Conflict-of-Interest Disclosure Form	90340-conflict-of-interest-statement.pdf
Copyright License Agreement	90340-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate	90340-non-native-speakers.pdf
Peer-review Report	90340-peer-reviews.pdf
Scientific Misconduct Check	93374-scientific-misconduct-check.png
Scientific Editor Work List	90340-scientific-editor-work-list.pdf
CrossCheck Report	90340-CrossCheck report.pdf