Publication Name	World Journal of Hepatology
Manuscript ID	90426
Country	Pakistan

Received	2023-12-03 18:24
Peer-Review Started	2023-12-03 18:24
First Decision by Editorial Office Director	2024-01-15 07:56
Return for Revision	2024-01-15 07:56
Revised	2024-01-16 17:20
Publication Fee Transferred
Second Decision by Editor	2024-02-22 02:34
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2024-02-22 03:26
Articles in Press	2024-02-22 03:26
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-03-13 23:58
Publish the Manuscript Online	2024-03-27 13:28

ISSN	1948-5182 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Editorial
Article Title	Is there a need for universal double reflex testing of HBsAg-positive individuals for hepatitis D infection?
Manuscript Source	Invited Manuscript
All Author List	Zaigham Abbas and Minaam Abbas
ORCID	Author(s) ORCID Number Zaigham Abbas http://orcid.org/0000-0002-9513-5324
Funding Agency and Grant Number
Corresponding Author	Zaigham Abbas, AGAF, FACG, FACP, FCPS, FRCP, FRCPE, Professor, Department of Hepatogastroenterology and Liver Transplantation, Dr. Ziauddin University Hospital, Clifton, Karachi 75600, Sindh, Pakistan. drzabbas@gmail.com
Key Words	Reflex testing; Hepatitis D; Hepatitis B; Hepatitis D virus RNA; HBsAg; Anti-hepatitis D virus antibody
Core Tip	Most countries lack high-quality hepatitis D virus (HDV) prevalence data, and published data are often biased by the collection techniques employed. Currently, HDV diagnosis practice is stepwise. It relies on physician’s discretion and requires numerous visits. Generally, only HBsAg-positive patients highly at risk for HDV are screened. Double reflex testing involves anti-HDV testing of all HBsAg-positive individuals, followed by HDV RNA testing for those who test positive for anti-HDV. This test is gaining attention because of the severe implications of HDV coinfection, emerging as an effective strategy for identifying undiagnosed cases.
Publish Date	2024-03-27 13:28
Citation	Abbas Z, Abbas M. Is there a need for universal double reflex testing of HBsAg-positive individuals for hepatitis D infection? World J Hepatol 2024; 16 (3): 300-303
URL	https://www.wjgnet.com/1948-5182/full/v16/i3/300.htm
DOI	https://dx.doi.org/10.4254/wjh.v16.i3.300

Full Article (PDF)	WJH-16-300-with-cover.pdf
Manuscript File	90426_Auto_Edited-YJP.docx
Answering Reviewers	90426-Answering reviewers.pdf
Audio Core Tip	90426-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	90426-Conflict-of-interest statement.pdf
Copyright License Agreement	90426-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	90426-Language certificate.pdf
Peer-review Report	90426-Peer-review(s).pdf
Scientific Misconduct Check	90426-CrossCheck.png
Scientific Misconduct Check	90426-Bing-Gong ZM-2.png
Scientific Editor Work List	90426-Scientific editor work list.pdf
CrossCheck Report	90426-CrossCheck report.pdf