Publication Name	World Journal of Diabetes
Manuscript ID	90456
Country	Kuwait

Received	2023-12-04 14:52
Peer-Review Started	2023-12-04 14:52
First Decision by Editorial Office Director	2024-01-23 06:25
Return for Revision	2024-01-23 06:25
Revised	2024-01-31 16:07
Publication Fee Transferred
Second Decision by Editor	2024-03-11 02:43
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2024-03-11 06:26
Articles in Press	2024-03-11 06:26
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-04-28 23:26
Publish the Manuscript Online	2024-05-10 11:51

ISSN	1948-9358 (online)
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Category	Endocrinology & Metabolism
Manuscript Type	Editorial
Article Title	Glucokinase regulatory protein rs780094 polymorphism is associated with type 2 diabetes mellitus, dyslipidemia, non-alcoholic fatty liver disease, and nephropathy
Manuscript Source	Invited Manuscript
All Author List	Ashraf Al Madhoun
ORCID	Author(s) ORCID Number Ashraf Al Madhoun http://orcid.org/0000-0001-8593-3878
Funding Agency and Grant Number	Funding Agency Grant Number Kuwait Foundation for the Advancement of Sciences (KFAS) and Dasman Diabetes Institute No. RACB-2021-007
Corresponding Author	Ashraf Al Madhoun, PhD, Academic Editor, Senior Scientist, Department of Genetics and Bioinformatics, Dasman Diabetes Institute, Jassim AlBahar Street, Dasman 15400, Kuwait. ashraf.madhoun@dasmaninstitute.org
Key Words	Glucokinase regulatory protein; rs780094; Type 2 diabetes mellitus; Dyslipidemia; Non-alcoholic fatty liver disease; Nephropathy
Core Tip	Genome-wide association studies have identified the glucokinase regulatory protein rs780094 variant as a risk factor for type 2 diabetes mellitus and its associated dyslipidemia, non-alcoholic fatty liver disease, and nephropathy. The precise mechanism of action remains elusive. Clinical evidence suggests that the variant impairs pancreatic β-cell function and disrupts hepatic triglyceride and glucose metabolism across various ethnicities.
Publish Date	2024-05-10 11:51
Citation	Al Madhoun A. Glucokinase regulatory protein rs780094 polymorphism is associated with type 2 diabetes mellitus, dyslipidemia, non-alcoholic fatty liver disease, and nephropathy. World J Diabetes 2024; 15(5): 814-817
URL	https://www.wjgnet.com/1948-9358/full/v15/i5/814.htm
DOI	10.4239/wjd.v15.i5.814

Full Article (PDF)	WJD-15-814-with-cover.pdf
Full Article (Word)	WJD-15-814.docx
Manuscript File	90456_Auto_Edited-YJP.docx
Answering Reviewers	90456-Answering reviewers.pdf
Audio Core Tip	90456-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	90456-Conflict-of-interest statement.pdf
Copyright License Agreement	90456-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	90456-Language certificate.pdf
Peer-review Report	90456-Peer-review(s).pdf
Scientific Misconduct Check	90456-Bing-Chen YL-2.png
Scientific Editor Work List	90456-Scientific editor work list.pdf
CrossCheck Report	90456-CrossCheck report.pdf