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Articles Published Processes
8/25/2014 5:12:00 PM | Browse: 1065 | Download: 874
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Received |
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2014-01-18 18:25 |
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Peer-Review Started |
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2014-01-19 13:42 |
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To Make the First Decision |
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2014-02-14 14:33 |
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Return for Revision |
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2014-02-18 11:36 |
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Revised |
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2014-02-27 22:25 |
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Second Decision |
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2014-05-05 09:26 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2014-05-05 09:54 |
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Articles in Press |
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2014-05-23 10:43 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2014-05-16 22:28 |
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Typeset the Manuscript |
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2014-07-01 15:00 |
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Publish the Manuscript Online |
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2014-07-21 17:17 |
Category |
Surgery |
Manuscript Type |
Meta-Analysis |
Article Title |
Role of Notch signaling pathway in gastric cancer: A meta-analysis of the literature
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Xiao Du, Zhong Cheng, Yi-Han Wang, Zi-Heng Guo, Si-Qin Zhang, Jian-Kun Hu and Zong-Guang Zhou |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
National Natural Science Foundation of China |
81071777 |
Sichuan Province Science and Technology Support Program |
2011SZ0293 |
Sichuan Province Science and Technology Support Program |
2011SZ0087 |
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Corresponding Author |
Jian-Kun Hu, Professor, Department of Gastrointestinal Surgery, West China Hospital, Sichuan University, No. 37, Guo Xue Xiang, Chengdu 610041, Sichuan Province, China. hujkwch@126.com |
Key Words |
Notch; Gastric cancer; Incidence; Prognosis; Meta-analysis |
Core Tip |
This article quantitatively summarizes the evidence for the association between Notch signaling pathway and gastric cancer (GC) by meta-analysis, and finds that Notch1 and Notch2 signaling pathways have been activated in GC; increased expression of Notch1 is associated with non-cardia location, > 5 cm size, diffuse type, positive lymphovascular invasion and distal metastasis; Notch1 and Jagged1 may be independent poor prognostic predictors in GC. Notch signaling may participate in tumor formation and progression of GC. |
Publish Date |
2014-07-21 17:17 |
Citation |
Du X, Cheng Z, Wang YH, Guo ZH, Zhang SQ, Hu JK, Zhou ZG. role of Notch signaling pathway in gastric cancer: A meta-analysis of the literature. World J Gastroenterol 2014; 20(27): 9191-9199 |
URL |
http://www.wjgnet.com/1007-9327/full/v20/i27/9191.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v20.i27.9191 |
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