Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	90533
Country	Spain

Received	2023-12-06 16:10
Peer-Review Started	2023-12-06 16:10
First Decision by Editorial Office Director	2024-01-06 07:14
Return for Revision	2024-01-06 07:14
Revised	2024-01-17 18:23
Publication Fee Transferred
Second Decision by Editor	2024-02-18 01:51
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2024-02-18 03:47
Articles in Press	2024-02-18 03:47
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-03-26 05:46
Publish the Manuscript Online	2024-04-11 02:23

ISSN	1948-5204 (online)
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Category	Oncology
Manuscript Type	Minireviews
Article Title	Mixed neuroendocrine non-neuroendocrine neoplasms in gastroenteropancreatic tract
Manuscript Source	Invited Manuscript
All Author List	Sebastián Díaz-López, Jerónimo Jiménez-Castro, Carlos Enrique Robles-Barraza, Carlos Ayala-de Miguel and Manuel Chaves-Conde
ORCID	Author(s) ORCID Number Sebastián Díaz-López http://orcid.org/0009-0001-7890-9682 Jerónimo Jiménez-Castro http://orcid.org/0000-0003-2618-1412 Carlos Enrique Robles-Barraza http://orcid.org/0009-0007-7881-6287 Carlos Ayala-de Miguel http://orcid.org/0009-0006-2897-1361 Manuel Chaves-Conde http://orcid.org/0000-0001-6412-5732
Funding Agency and Grant Number
Corresponding Author	Jerónimo Jiménez-Castro, MD, Staff Physician, Medical Oncology Department, Hopsital Universitario Valme, Ctra. de Cádiz Km. 548.9, C.P., Seville 41014, Andalucía, Spain. jerojc@gmail.com
Key Words	Mixed neuroendocrine non-neuroendocrine neoplasms; Mixed adeno-neuroendocrine carcinomas; Mixed tumours; Gastroenteropancreatic; Treatment; Etiology; Diagnosis
Core Tip	In this review we try to clarify definition of mixed neuroendocrine (NE) non-NE tumours that have been changed along past years and analyze available evidence about their diagnosis and treatment options according to their location and extension. We have to bear in mind that we do not have validated protocols or clinical guidelines on the management of this group of diseases, although most authors propose treating mixed NE non-NE neoplasm with the high-grade NE component as treatment target. In any case, the lack of high-quality scientific evidence, based on randomised clinical trials, makes it essential to deepen our knowledge of this group of neoplasms.
Publish Date	2024-04-11 02:23
Citation	Díaz-López S, Jiménez-Castro J, Robles-Barraza CE, Ayala-de Miguel C, Chaves-Conde M. Mixed neuroendocrine non-neuroendocrine neoplasms in gastroenteropancreatic tract. World J Gastrointest Oncol 2024; 16(4): 1166-1179
URL	https://www.wjgnet.com/1948-5204/full/v16/i4/1166.htm
DOI	https://dx.doi.org/10.4251/wjgo.v16.i4.1166

Full Article (PDF)	WJGO-16-1166-with-cover.pdf