Publication Name	World Journal of Hepatology
Manuscript ID	9055
Country	Argentina

Received	2014-01-18 18:49
Peer-Review Started	2014-01-18 20:12
To Make the First Decision	2014-02-13 16:18
Return for Revision	2014-02-20 23:13
Revised	2014-03-08 01:08
Second Decision	2014-05-14 16:29
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-05-14 16:42
Articles in Press	2014-05-23 12:23
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-07-01 12:13
Publish the Manuscript Online	2014-07-04 18:01

ISSN	1948-5182 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Challenge of liver disease in systemic lupus erythematosus: Clues for diagnosis and hints for pathogenesis
Manuscript Source	Invited Manuscript
All Author List	Fernando Bessone, Natalia Poles and Marcelo G Roma
Funding Agency and Grant Number
Corresponding Author	Dr. Fernando Bessone, Gastroenterology and Hepatology Department, University of Rosario School of Medicine, Alvear 740, 1st floor, Rosario, 2000, Argentina. bessonefernando@gmail.com
Key Words	Systemic lupus erythematosus; Lupus hepatitis; Esteatosis; Regenerative nodular hyperplasia; Hepatitis C; Autoinmmune hepatitis; Hepatotoxicity; Nonsteroidal anti-inflammatory drugs; Methotrexate
Core Tip	The existence of liver disease associated with lupus itself, or increased susceptibility to concomitant liver diseases, either autoimmune or non-autoimmune ones, is still somewhat controversial, and difficult to diagnose. Data in the literature are scarce, and often based on case reports or clinical studies with limited patient size or histological evidence. The pros and cons to support the existence of such pathological entities, and the still preliminary studies on the mechanisms involved are critically discussed here. We concluded that liver is often a target of systemic lupus erythematosus (SLE), and biochemical liver tests should be systematically carried out in these patients.
Publish Date	2014-07-04 18:01
Citation	Bessone F, Poles N, Roma MG. Challenge of liver disease in systemic lupus erythematosus: Clues for diagnosis and hints for pathogenesis. World J Hepatol 2014; 6(6): 394-409
URL	http://www.wjgnet.com/1948-5182/full/v6/i6/394.htm
DOI	http://dx.doi.org/10.4254/wjh.v6.i6.394

Full Article (PDF)	WJH-6-394.pdf
Full Article (Word)	WJH-6-394.doc
Manuscript File	9055-Review.doc
Answering Reviewers	9055-Answering reviewers.pdf
Copyright License Agreement	9055-Copyright assignment.pdf
Peer-review Report	9055-Peer review(s).pdf
Scientific Editor Work List	9055-Scientific editor work list.pdf