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Articles Published Processes
6/15/2024 2:49:03 AM | Browse: 129 | Download: 645
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Received |
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2023-12-07 05:59 |
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Peer-Review Started |
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2023-12-07 05:59 |
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First Decision by Editorial Office Director |
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2024-02-06 22:08 |
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Return for Revision |
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2024-02-06 22:08 |
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Revised |
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2024-02-13 09:13 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2024-04-01 01:39 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2024-04-01 02:25 |
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Articles in Press |
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2024-04-01 02:25 |
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Edit the Manuscript by Language Editor |
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2024-04-07 02:28 |
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Typeset the Manuscript |
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2024-05-14 12:41 |
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Publish the Manuscript Online |
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2024-06-15 02:49 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Minireviews |
| Article Title |
Therapeutic strategies for targeting the epidermal growth factor receptor signaling pathway in metastatic colorectal cancer
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yi Zhou, Shuang Wu and Fan-Jie Qu |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Fan-Jie Qu, Doctor, MD, Chief Physician, Professor, Department of Oncology, Affiliated Dalian Third People’s Hospital of Dalian Medical University, No. 40 Qianshan Road, Dalian 116033, Liaoning Province, China. wyb960419@163.com |
| Key Words |
Metastatic colorectal cancer; Epidermal growth factor receptor; B-type RAF mutation; Kirsten rat sarcoma viral oncogene wild type; Kirsten rat sarcoma viral oncogene G12C mutation; Human epidermal growth factor receptor 2 overexpression/amplification |
| Core Tip |
My review focuses on targeted therapies on the epidermal growth factor receptor (EGFR) signaling pathway in metastatic colorectal cancer, mainly includes: (1) Treatment targeting rat sarcoma (RAS) status, including RAS wild type, maintenance therapy of (EGFR monoclonal antibody, re-challenge of anti-EGFR therapy, treatment of NoeRAS and Kirsten RAS viral oncogene G12C mutations; (2) treatment of patients with B-type RAF mutations; and (3) treatment of human EGFR 2 amplification or overexpression. |
| Publish Date |
2024-06-15 02:49 |
| Citation |
Zhou Y, Wu S, Qu FJ. Therapeutic strategies for targeting the epidermal growth factor receptor signaling pathway in metastatic colorectal cancer. World J Gastrointest Oncol 2024; 16(6): 2362-2379 |
| URL |
https://www.wjgnet.com/1948-5204/full/v16/i6/2362.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v16.i6.2362 |
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