Publication Name	World Journal of Gastroenterology
Manuscript ID	90562
Country	Japan

Received	2023-12-07 08:45
Peer-Review Started	2023-12-07 08:45
First Decision by Editorial Office Director	2024-01-24 05:06
Return for Revision	2024-01-24 05:06
Revised	2024-02-05 02:12
Publication Fee Transferred
Second Decision by Editor	2024-03-25 01:21
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2024-03-25 01:54
Articles in Press	2024-03-25 01:54
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-04-03 03:04
Publish the Manuscript Online	2024-04-12 16:45

ISSN	1007-9327 (print) and 2219-2840 (online)
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Category	Gastroenterology & Hepatology
Manuscript Type	Observational Study
Article Title	Preoperative albumin-bilirubin score and liver resection percentage determine postoperative liver regeneration after partial hepatectomy
Manuscript Source	Invited Manuscript
All Author List	Kazuhiro Takahashi, Masahiko Gosho, Yoshihiro Miyazaki, Hiromitsu Nakahashi, Osamu Shimomura, Kinji Furuya, Manami Doi, Yohei Owada, Koichi Ogawa, Yusuke Ohara, Yoshimasa Akashi, Tsuyoshi Enomoto, Shinji Hashimoto and Tatsuya Oda
ORCID	Author(s) ORCID Number Kazuhiro Takahashi http://orcid.org/0000-0003-1089-0644 Masahiko Gosho http://orcid.org/0000-0002-5973-9163 Yoshihiro Miyazaki http://orcid.org/0000-0002-1851-964X Hiromitsu Nakahashi http://orcid.org/0000-0004-6419-0744 Osamu Shimomura http://orcid.org/0000-0002-1735-5057 Kinji Furuya http://orcid.org/0000-0002-2630-3072 Manami Doi http://orcid.org/0000-0002-8731-3733 Yohei Owada http://orcid.org/0000-0003-4979-7236 Koichi Ogawa http://orcid.org/0000-0002-5710-4324 Yusuke Ohara http://orcid.org/0000-0001-6807-6261 Yoshimasa Akashi http://orcid.org/0000-0003-0589-3816 Tsuyoshi Enomoto http://orcid.org/0000-0003-0540-2239 Shinji Hashimoto http://orcid.org/0000-0003-3323-4594 Tatsuya Oda http://orcid.org/0000-0001-6115-0158
Funding Agency and Grant Number
Corresponding Author	Kazuhiro Takahashi, FACS, MD, PhD, Assistant Professor, Surgeon, Department of Gastrointestinal and Hepatobiliary-Pancreatic Surgery, University of Tsukuba, Tennodai 1-1-1, Tsukuba 3058-575, Ibaraki, Japan. kazu1123@md.tsukuba.ac.jp
Key Words	Liver regeneration; Albumin-bilirubin score; Liver resection percentage; Partial hepatectomy; Human; Regeneration index
Core Tip	Insights into posthepatectomy liver regeneration in humans are limited. We quantified liver volumes using the latest volumetric software and investigated perioperative factors that affect posthepatectomy liver regeneration. It was revealed that liver regeneration continues after 3 months of hepatectomy with more than one-fourth of the liver resection and decline in preoperative liver function, reflected by the albumin-bilirubin (ALBI) score, is associated with decreased regeneration. Furthermore, restoring to the original volume depended on the combination of the preoperative ALBI score and liver resection percentage. With this knowledge, surgeons can select an appropriate hepatectomy type with rehepatectomy in mind after intrahepatic recurrence.
Publish Date	2024-04-12 16:45
Citation	Takahashi K, Gosho M, Miyazaki Y, Nakahashi H, Shimomura O, Furuya K, Doi M, Owada Y, Ogawa K, Ohara Y, Akashi Y, Enomoto T, Hashimoto S, Oda T. Preoperative albumin-bilirubin score and liver resection percentage determine postoperative liver regeneration after partial hepatectomy. World J Gastroenterol 2024; 30(14): 2006-2017
URL	https://www.wjgnet.com/1007-9327/full/v30/i14/2006.htm
DOI	https://dx.doi.org/10.3748/wjg.v30.i14.2006

Full Article (PDF)	WJG-30-2006-with-cover.pdf
STROBE Statement	90562-STROBE statement.pdf
Manuscript File	90562_Auto_Edited-YJP.docx
Answering Reviewers	90562-Answering reviewers.pdf
Audio Core Tip	90562-Audio core tip.m4a
Biostatistics Review Certificate	90562-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	90562-Conflict-of-interest statement.pdf
Copyright License Agreement	90562-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s)	90562-Informed consent statement.pdf
Institutional Review Board Approval Form or Document	90562-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	90562-Language certificate.pdf
Supplementary Material	90562-Supplementary material.pdf
Peer-review Report	90562-Peer-review(s).pdf
Scientific Misconduct Check	90562-Bing-Li L-2.png
CrossCheck Report	90562-CrossCheck.png
CrossCheck Report	90562-CrossCheck report.pdf