Publication Name	World Journal of Hepatology
Manuscript ID	90585
Country	China

Received	2023-12-07 15:40
Peer-Review Started	2023-12-07 15:40
To Make the First Decision
Return for Revision	2024-02-23 06:18
Revised	2024-02-26 13:05
Second Decision	2024-04-07 02:40
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-04-07 04:52
Articles in Press	2024-04-07 04:52
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-05-11 02:54
Publish the Manuscript Online	2024-05-22 11:33

ISSN	1948-5182 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Microbiology
Manuscript Type	Review
Article Title	Multifunctional role of oral bacteria in the progression of non-alcoholic fatty liver disease
Manuscript Source	Invited Manuscript
All Author List	En-Hua Mei, Chao Yao, Yi-Nan Chen, Shun-Xue Nan and Sheng-Cai Qi
ORCID	Author(s) ORCID Number Sheng-Cai Qi http://orcid.org/0000-0001-5015-0662
Funding Agency and Grant Number
Corresponding Author	Sheng-Cai Qi, PhD, Attending Doctor, Department of Prothodontics, Shanghai Stomatological Hospital, Fudan University, No. 356 East Beijing Road, Shanghai 200000, China. dentistqi@163.com
Key Words	Non-alcoholic fatty liver disease; Oral bacteria; Gut bacteria; Periodontitis; Non-alcoholic steatohepatitis
Core Tip	Non-alcoholic fatty liver disease (NAFLD) is a significant concern within the realm of chronic liver diseases, notably affecting economic health. The disruption of intestinal flora balance by oral bacteria accelerates the progression of NAFLD. Moreover, through the inflamed oral mucosa, these bacteria and their virulence factors may enter the bloodstream, leading to systemic inflammation. Therefore, an innovative therapeutic approach for NAFLD involves strategic adjustments to the microbial balance within the oral cavity and gastrointestinal tract. This review succinctly delineates the roles and mechanisms of oral bacteria in NAFLD, providing a foundational framework for future therapeutic strategies.
Publish Date	2024-05-22 11:33
Citation	<p>Mei EH, Yao C, Chen YN, Nan SX, Qi SC. Multifunctional role of oral bacteria in the progression of non-alcoholic fatty liver disease. <i>World J Hepatol</i> 2024; 16(5): 688-702</p>
URL	https://www.wjgnet.com/1948-5182/full/v16/i5/688.htm
DOI	https://dx.doi.org/10.4254/wjh.v16.i5.688

Full Article (PDF)	WJH-16-688-with-cover.pdf
Manuscript File	90585_Auto_Edited-YJP.docx
Answering Reviewers	90585-Answering reviewers.pdf
Audio Core Tip	90585-Audio core tip.MP3
Conflict-of-Interest Disclosure Form	90585-Conflict-of-interest statement.pdf
Copyright License Agreement	90585-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	90585-Language certificate.pdf
Peer-review Report	90585-Peer-review(s).pdf
Scientific Misconduct Check	90585-Bing-Chen YL-2.png
Scientific Editor Work List	90585-Scientific editor work list.pdf
CrossCheck Report	90585-CrossCheck report.pdf